Analysis of DNA methylation in cancer: location revisited

Analysis of DNA methylation in cancer: location revisitedAnalysis of DNA methylation in cancer: location revisited, Published online: 17 April 2018; doi:10.1038/s41571-018-0004-4Despite extensive research efforts, very few DNA methylation-based biomarkers have been implemented clinically. In this Perspective, the authors describe the importance of considering the genomic locations examined in determining the diagnostic or prognostic relevance of putative DNA methylation-based biomarkers.

Source: Nature Clinical Practice Oncology - April 17, 2018 Category: Cancer & Oncology Authors: Alexander Koch Sophie C. Joosten Zheng Feng Tim C. de Ruijter Muriel X. Draht Veerle Melotte Kim M. Smits Jurgen Veeck James G. Herman Leander Van Neste Wim Van Criekinge Tim De Meyer Manon van Engeland Source Type: research