Change in muscle volume after steroid therapy in patients with myositis assessed using cross-sectional computed tomography

Steroid therapy, a key therapy for inflammatory, allergic, and immunological disorders, is often associated with steroid myopathy as one of the side effects. Steroid therapy is considered the first-line therap...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research

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Publication date: Available online 19 December 2019Source: IDCasesAuthor(s): Yuki Tokuyama, Takeshi Matsumoto, Yusuke Kusakabe, Naoki Yamamoto, Kensaku Aihara, Shinpachi Yamaoka, Michiaki MishimaAbstractA paradoxical reaction (PR) is an excessive immune response occurring during antitubercular therapy (ATT), but is rare in patients with miliary tuberculosis. A 78-year-old woman complained of general malaise, loss of appetite, and fever for 10 days. Chest computed tomography (CT) showed diffuse, bilateral, discrete miliary nodules. The patient was treated with ATT for miliary tuberculosis. Nine days after starting the treat...
Source: IDCases - Category: Infectious Diseases Source Type: research
Authors: Watanabe H, Kitahara Y, Murakami Y, Nihashi F, Matsushima S, Eifuku T, Uto T, Sato J, Imokawa S, Suda T Abstract We herein report a 38-year-old woman with breast cancer who developed Pneumocystis jirovecii pneumonia (PCP) during neoadjuvant dose-dense chemotherapy combined with dexamethasone as antiemetic therapy. Chest computed tomography showed bilateral ground-glass opacities and consolidation. The serum β-D-glucan levels were elevated, and P. jirovecii DNA was detected from the bronchoalveolar lavage fluid by polymerase chain reaction. Her clinical findings improved with trimethoprim/sulfamethoxaz...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
We present the case of a 55-year-old woman with known emphysema, who was referred to us for progressive respiratory failure that was unresponsive to therapy. The patient had 9 hospital admissions in the preceding 5 months and was treated with multiple courses of antibiotics and systemic steroid therapy for a diagnosis of cryptogenic organizing pneumonia. The steroid therapy was complicated by 51 pounds of weight gain. She had conversational as well as profound exertional shortness of breath. Physical examination revealed a woman in moderate distress and bilateral diffuse wheezing and rhonchi. Computed tomography of the che...
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Tags: Am J Med Sci Source Type: research
ConclusionsMyocardial perfusion was recovered by steroid therapy in 61% and preserved in 8% of patients. Myocardial perfusion recovery after steroid therapy was significantly associated with a low incidence of MACE.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
ConclusionsThis case highlights the need for careful consideration of patient medication history while evaluating the possible differential diagnoses that may contribute to a patient ’s presentation.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Herein, we report a case of immunoglobulin A vasculitis (IgAV) onset in an elderly patient. A 61-year-old male presented to our hospital with palpable purpura on his right leg and abdomen and diffuse abdominal pain. Computed tomography revealed thickened intestinal wall and ascites. In addition, his serum IgA and urinary protein levels were elevated. The histopathological finding of palpable purpura indicated vasculitis, and he was diagnosed with IgAV. Accordingly, steroid therapy was initiated. Gradually, purpura and abdominal pain disappeared, and he was discharged on day 26 after admission. Although IgAV is common in ch...
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
CONCLUSIONS: Pericardial effusion with cardiac tamponade is a difficult diagnosis even with ultrasound. Lactate levels, central venous pressure plus venous saturation, and brain natriuretic peptide could help in early detection. PMID: 31248337 [PubMed - in process]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
We present a middle-aged white male who exemplifies this unique presentation with new onset recurrent otitis media and mastoiditis, which did not respond to repeated courses of antibiotics requiring mastoidectomy and myringotomy tube placement. On chest x-ray, he was found to have multiple lung nodules that was followed by a computed tomography (CT) scan of his chest and CT guided biopsy which revealed granulomatous inflammation and necrosis, consistent with GPA. Autoimmune laboratory work-up was also suggestive of GPA. The patient had complete resolution of symptoms with steroid therapy. This case reinforces the concept o...
Source: Archives of Iranian Medicine - Category: Middle East Health Authors: Tags: Arch Iran Med Source Type: research
377Objectives: Single photon emission computed tomography (SPECT) perfusion imaging is useful for diagnosis of cardiac sarcoidosis (CS). Phase analysis by using electrocardiography (ECG)-gated SPECT perfusion imaging reflects the dyssynchrony of left ventricular (LV) wall motion as well as the heterogeneity of perfusion defects in terms of its extent. We previously reported that phase analysis using ECG-gated SPECT perfusion imaging can predict the adverse cardiac events in patients with CS. Our aim is to evaluatethe effect of steroid therapy on phase analysis in CS patients. Methods: Thirty-two consecutive patients with d...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Cardiovascular Clinical Science: Infiltrative Cardiomyopathies and Infection Imaging Source Type: research
Authors: Koda R, Tsuchida M, Iino N, Murata M, Inui K, Nakagawa Y, Nishiyama T, Ikeda Y, Hasegawa G, Oguma F, Narita I Abstract A 56-year-old man was referred to our facility after developing edema in his right leg. Enhanced computed tomography (CT) revealed a periarterial soft tissue mass surrounding the right iliac artery compressing the iliac vein. His elevated serum IgG4 level indicated IgG4-related disease (IgG4-RD). Both a percutaneous and surgical biopsy of this periarterial lesion proved challenging and were not pursued. A prostate biopsy, however, finally provided a histological diagnosis of IgG4-RD. Oral ...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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