Alcohol price law 'important tool' in tackling drinking

Wales' health secretary urges assembly members to back the bill ahead of a Senedd debate.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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ConclusionMS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This study aimed to investigate the effect of silibinin on CFLAR-JNK pathway in NASH models both in vivo and in vitro. The in vivo study was performed using male C57BL/6 mice fed with methionine– choline-deficient diet and simultaneously treated with silibinin for 6 weeks. The in vitro study was performed by using mouse NCTC-1469 cells which were respectively pretreated with oleic acid plus palmitic acid, and adenovirus-down Cflar for 24 h, then treated with silibinin for 24 h. After the drug treatment, the key indicators involved in CFLAR-JNK pathway including hepatic injury, lipid metabolism and oxidative...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Publication date: Available online 21 February 2019Source: Food Quality and PreferenceAuthor(s): J. Delarue, A.-C. Brasset, F. Jarrot, F. Abiven
Source: Food Quality and Preference - Category: Food Science Source Type: research
ConclusionsA high prevalence of drugs of abuse was identified in a cohort of victims of violent death. Objective drug trends observed were consistent with national self-reported rehabilitation centre data and research on self-reported drug user. This study was limited by the sampling strategy, including challenges associated with obtaining consent and the rapid turnover of violent fatalities. Despite this – and to the authors’ knowledge – this study provided the first prospective post-mortem toxicological investigation into violent death in South Africa. Contextually, it highlights the need for routine an...
Source: Journal of Forensic and Legal Medicine - Category: Forensic Medicine Source Type: research
Publication date: Available online 21 February 2019Source: Journal of Forensic and Legal MedicineAuthor(s): Lin-Lin Wang, Miao Zhang, Wei Zhang, Bing-Xuan Li, Ru-Bo Li, Bao-Li Zhu, Xu Wu, Da-Wei Guan, Guo-Hua Zhang, Rui ZhaoAbstractAcute poisoning is a public health threat that leads to morbidity and mortality worldwide. In this retrospective study, we evaluated autopsies from deaths caused by acute poisoning from 2008 to 2017 at the School of Forensic Medicine, China Medical University (SFMCMU) in the Liaoning Province, northeast China. A total of 140 poisoning deaths were investigated and the demographic characteristics,...
Source: Journal of Forensic and Legal Medicine - Category: Forensic Medicine Source Type: research
Publication date: Available online 21 February 2019Source: Journal of Physics and Chemistry of SolidsAuthor(s): Sha Li, Yahui Chang, Gaoyi Han, Hua Song, Yunzhen Chang, Yaoming XiaoAbstractCarbon sponges enclosing carbon fibers are prepared by carbonizing the melamine sponges with bunches of carbon fibers sewn in, and used as the substrate and current collector to fabricate asymmetric supercapacitors. MnO2/rGO/CS-CFs as the positive electrode and the PPy/CS-CFs as the negative electrode have been prepared and characterized, and in LiCl/polyvinyl alcohol gel electrolyte, the positive and negative electrodes are used to fabr...
Source: Journal of Physics and Chemistry of Solids - Category: Physics Source Type: research
Publication date: Available online 21 February 2019Source: The LancetAuthor(s): Alistair Story, Robert W Aldridge, Catherine M Smith, Elizabeth Garber, Joe Hall, Gloria Ferenando, Lucia Possas, Sara Hemming, Fatima Wurie, Serena Luchenski, Ibrahim Abubakar, Timothy D McHugh, Peter J White, John M Watson, Marc Lipman, Richard Garfein, Andrew C HaywardSummaryBackgroundDirectly observed treatment (DOT) has been the standard of care for tuberculosis since the early 1990s, but it is inconvenient for patients and service providers. Video-observed therapy (VOT) has been conditionally recommended by WHO as an alternative to DOT. W...
Source: The Lancet - Category: General Medicine Source Type: research
In this study, we developed a comprehensive and reliable analytical method to qualitatively analyze the components in NLXTD. This novel method was based on three-dimensional ultra-fast high performance liquid chromatography coupled with diode array detector (3D-UPLC-DAD) with an additional component validation method via incorporation of the mixture standard compounds during the verification step. In addition, the relationship between active components and “Monarch drug, Minster drug, Assistant drug, Guide drug” were determined. Our results showed that gradient elution with the mobile phase of 0.02% formic acid...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: Most participants reported having healthy life habits, which they believe influence on disease control. Among the investigated parameters, only the habit of not smoking was associated with the absence of hypertensive peaks; the other habits did not present statistical association with the comorbidities. PMID: 30785546 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
ConclusionsMindfulness-based CSB interventions should evaluate the benefit of increasing intentional responses towards present-moment experiences among adults with SUD. Targeting alcohol/drug misuse, negative affect, and judgment towards thoughts and emotions may be beneficial.
Source: Mindfulness - Category: Psychiatry & Psychology Source Type: research
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