Focus on FOCUS, a new DWI-MRI protocol for breast lesions
A new type of diffusion-weighted imaging (DWI) is giving conventional breast...Read more on AuntMinnie.comRelated Reading: Breast MRI technique helps cancer detection without contrast Preoperative breast MRI: More help than harm Short is just as sweet for breast MRI protocol Novel breast MRI technique could reduce biopsy rate CT, MRI contribute to major shake-up in breast imaging
Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer, Published online: 21 June 2018; doi:10.1038/s41397-018-0030-8Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer
Well-balanced levels of tyrosine phosphorylation, maintained by the reversible and coordinated actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), are critical for a wide range of cellular processes including growth, di ﬀerentiation, metabolism, migration, and survival. Aberrant tyrosine phosphorylation, as a result of a perturbed balance between the activities of PTKs and PTPs, is linked to the pathogenesis of numerous human diseases, including cancer, suggesting that PTPs may be innovative molecular targets for cancer treatment. Two PTPs that have an important inhibitory role in haemato...
The study is potentially a “leap forward” in cancer genomics, particularly for subsets of patients with metastatic and anaplastic thyroid cancer.
In the Utah Cancer Survivors Study, male thyroid cancer survivors had an almost 50% higher risk of developing cardiovascular disease than females.
AbstractDespite significant advances in our ability to treat cancer, cytotoxic chemotherapy continues to be the mainstay treatment for many solid tumours. Chemotherapy is commonly associated with a raft of largely manageable adverse events; however, gastrointestinal (GI) toxicity (also termed mucositis) remains a significant challenge with little in the way of preventative and therapeutic options. The inability to manage GI complications likely reflects our incomplete understanding of its aetiology and the idiosyncrasies of each chemotherapeutic agent. This review highlights aims to provide a narrative for the involvement ...
Saby George, MD, FACP, Roswell Park Cancer Institute, shares CARMENA Study Results | Sunitinib Not Inferior to Sunitinib Following Nephrectomy at ASCO 2018 Author: Annual-Meeting Added: 06/20/2018
Saby George, MD, FACP, Roswell Park Cancer Institute, explains Checkmate-214 has a Higher Response Rate | 9% of Patients Went on to Complete Response at ASCO 2018 Author: Annual-Meeting Added: 06/20/2018
Conclusions: A majority of ESD for EGC were performed in tertiary care hospitals in Korea. The clinical status showed excellent clinical outcomes and did not differ by the year and between the types of hospitals in Korea. PMID: 29921044 [PubMed - as supplied by publisher]
Funding for research that seeks to identify, develop, test, evaluate and/or refine strategies to disseminate and implement evidence-based practices into public health, clinical practice, and community settings. This program is featured in the Division of Cancer Control and Population Sciences Selected List of Funding Opportunities Relevant to Rural Cancer Control. Geographic coverage: Nationwide -- National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services
Saby George, MD, FACP, Roswell Park Cancer Institute, explains Update on Checkmate-214 Study | Approval of Nivolumab &Ipilimumab Combination at ASCO 2018 Author: Annual-Meeting Added: 06/20/2018