MRI findings of low-grade fibromyxoid sarcoma: a case report and literature review

Low-grade fibromyxoid sarcoma (LGFMS) is a distinctive slow growing soft tissue neoplasm, mostly affecting young individuals with no gender difference. It usually arises in deep soft tissue of the lower limbs ...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Case report Source Type: research

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Conditions:   Sarcoma;   Advanced Sarcoma;   High Grade Sarcoma Interventions:   Drug: DCC-3014;   Drug: Avelumab Sponsor:   Memorial Sloan Kettering Cancer Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractPurposePancreatic tumors are rare in children and limited data are available regarding incidence, treatment, and outcomes. We aim to describe patient and tumor characteristics and to report on survival of these diseases.MethodsChildren with pancreatic tumors were queried from the National Cancer Database (2004 –2014). The association between treatment and hazard of death was assessed using Kaplan–Meier method and Cox regression model.ResultsWe identified 109 children with pancreatic tumors; 52% were male and median age at diagnosis was 14  years. Tumors were distributed as follows: pseudopapillary ...
Source: Pediatric Surgery International - Category: Surgery Source Type: research
Authors: Álvarez Álvarez R, Cruz Jurado J, Del Muro Solans XG, Giner JL, López Pousa A, Martín-Broto J, Valverde CM Abstract Soft tissue sarcomas (STS) constitute a heterogeneous group of rare solid tumors associated with significant morbidity and mortality. The evaluation and treatment of STS require a multidisciplinary team with extensive experience in the management of these types of tumors. National and international clinical practice guidelines for STS do not always provide answers to a great many situations that specialists have to contend with in their everyday practice. This cons...
Source: Sarcoma - Category: Cancer & Oncology Tags: Sarcoma Source Type: research
Conclusions: Endovascular brachytherapy is a novel, safe and effective therapeutic modality for non-resectable primary cardiac sarcomas either for palliation of obstruction, or tumor mass reduction to allow complete resection. PMID: 31969917 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Authors: Kind S, Merenkow C, Büscheck F, Möller K, Dum D, Chirico V, Luebke AM, Höflmayer D, Hinsch A, Jacobsen F, Göbel C, Weidemann S, Fraune C, Möller-Koop C, Hube-Magg C, Clauditz TS, Simon R, Sauter G, Wilczak W, Bawahab AA, Izbicki JR, Perez D, Marx A Abstract Syndecan-1 (CD138) is a transmembrane proteoglycan known to be expressed in various normal and malignant tissues. It is of interest because of a possible prognostic role of differential expression in tumors and its role as a target for indatuximab, a monoclonal antibody coupled with a cytotoxic agent. To comprehensively analyze ...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Approval marks the first for a drug to treat this rare soft tissue sarcoma
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Oncology, Pharmacy, FDA Approvals, Source Type: news
Conditions:   Advanced Non Small Cell Lung Cancer;   Uterine Cancer;   Soft Tissue Sarcoma Interventions:   Drug: PD-1 inhibitor;   Drug: Apatinib Sponsors:   Hunan Cancer Hospital;   Jiangsu HengRui Medicine Co., Ltd. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Oncology News Burst
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
Hand and wrist soft tissue masses comprise a special subset of soft tissue masses. Lesion prevalence always should be considered. The World Health Organization tumor database reveals soft tissue masses of the hand and wrist are much more common than osseous lesions. In clinical practice, pseudotumors are much more common than neoplasms. Benign tumors of soft tissue are much more common than malignant tumors, with an annual incidence of benign tumors of up to 3000 per million population.1 Malignant sarcomas are extremely rare (50 cases per million per year).1 Understanding available imaging modalities and imaging characteri...
Source: Contemporary Diagnostic Radiology - Category: Radiology Tags: ARTICLE Source Type: research
Authors: Chung YH, Jang JW, Cho JY Abstract Malignant peripheral nerve sheath tumor (MPNST) is a rare and often aggressive soft tissue sarcoma originating from the sheaths of peripheral nerves. Approximately 50% of MPNSTs occur in patients with neurofibromatosis (NF). These tumors often present as deep soft tissue lesions, arising from the nerve plexuses of the extremities or from the nerves extending from the trunk. They rarely occur in the skin, especially in patients with NF. Herein, we report our experience with an MPNST of the skin in a patient with NF. PMID: 31964130 [PubMed]
Source: Archives of Plastic Surgery - Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research
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