Log in to search using one of your social media accounts:

 

Widely Used COPD Meds Tied to Increased Fracture Risk

Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Orthopedics, Pulmonology, Rheumatology, Geriatrics, News, Source Type: news

Related Links:

Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Source Type: news
Authors: Liu L, Wang JL, Xu XY, Feng M, Hou Y, Chen L Abstract OBJECTIVE: Leukotriene receptor antagonists (LTRA), the anti-inflammatory agents, have been reported new therapeutic value in chronic obstructive pulmonary disease (COPD). However, the effects of LTRA on lung function decline in COPD were determined with inconsistent results and a meta-analysis is needed. MATERIALS AND METHODS: Published cohort or randomized controlled studies were retrieved from PubMed and Embase databases. RESULTS: Pooled standardized mean difference (SMD) with 95% confidence interval (CI) was calculated in a random effects mo...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Publication date: Available online 21 February 2018 Source:The Lancet Respiratory Medicine Author(s): Gregory A Payne, J Michael Wells
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
This study is registered with ClinicalTrials.gov, number NCT02442206. Findings Between May 18, 2015, and April 20, 2017, we randomly assigned 62 eligible participants to treatment; 30 to indacaterol–glycopyrronium followed by placebo and 32 to placebo followed by indacaterol–glycopyrronium. The 62 randomly assigned patients were included in the intent-to-treat analysis. There were two protocol violations and therefore 60 were included in the per-protocol analysis. 57 patients completed both treatment periods. After indacaterol–glycopyrronium treatment, left-ventricular end-diastolic volume increased from ...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
CONCLUSIONS: Telemonitoring of patients with COPD combined with home hospitalization may allow for a reduction in healthcare costs, although its usefulness in preventing exacerbations is still unclear. PMID: 29460648 [PubMed - as supplied by publisher]
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
This study aimed to increase our understanding of processes that underlie the effect of care pathway implementation on reduced 30-day readmission rate. Adherence to evidence-based recommendations, teamwork and burnout have previously been identified as potential mechanisms in this association. We conducted a secondary data analysis of 257 patients admitted with chronic obstructive pulmonary disease exacerbation and 284 team members caring for these patients in 19 Belgian, Italian and Portuguese hospitals. Clinical measures included 30-day readmission and adherence to a specific set of five care activities. Teamwork measure...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Authors: Yang L, Jiao X, Wu J, Zhao J, Liu T, Xu J, Ma X, Cao L, Liu L, Liu Y, Chi J, Zou M, Li S, Xu J, Dong L Abstract Cordyceps sinensis is a traditional Chinese herbal medicine that has been used for centuries in Asia as a tonic to soothe the lung for the treatment of respiratory diseases. The aim of the present study was to determine the effects of C. sinensis on airway remodeling in chronic obstructive pulmonary disease (COPD) and investigate the underlying molecular mechanisms. Rats with COPD were orally administered C. sinensis at low, moderate or high doses (2.5, 5 or 7.5 g/kg/day, respectively) for 12 wee...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Wu J, Li X, Qin Y, Cheng J, Hao G, Jin R, Zhu C Abstract The aim of the present study was to investigate the effect of a Traditional Chinese Herbal Medicine (TCHM), named Jinwei Tang on histone deacetylase 2 (HDAC2) and its role in the regulation of corticosteroid resistance in a rat model of chronic obstructive pulmonary disease (COPD). Male Wistar rats were divided into five groups (each n=10): COPD group, established by the intratracheal instillation of lipopolysaccharide and passive smoke exposure, and control, budesonide, theophylline + budesonide and Jinwei Tang + budesonide groups. Lung function was...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Luo X, Shi W, Zhang X, Yang X, Wang W, Zeng C, Wang H Abstract An elderly male patient with coronary heart disease underwent coronary angiography, which revealed bilateral severe coronary artery stenosis. Four stents were implanted, and at 5 h post-surgery, typical hemorrhagic shock appeared. Echocardiography verified heavy bleeding in the right thoracic cavity. Emergency angiography excluded injury or perforation of the coronary artery, aorta, right subclavian artery and brachiocephalic artery. Considering the patient's history of chronic obstructive pulmonary disease and severe cough during the operation...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhou X, Yi D, Wu Y, Pei X, Yu H, Chen Y, Jiang Y, Li W Abstract Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and loss of lung function. The present study aimed to investigate the diaphragmatic protein expression of myostatin and its correlation with apoptosis in a rat model of CPOD. Sprague Dawley rats were randomly divided into a control group and a COPD group, the latter of which were exposed to cigarette smoke to build a rat model of COPD. The validity of the COPD model was evaluated by assessment of lung function and histopathological analysis. Diaphra...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
More News: Chronic Obstructive Pulmonary | Geriatrics | Orthopaedics | Respiratory Medicine | Rheumatology