Women Who Are Most at Risk of Stroke

Stroke affects 55,000 more women than men each year in the United States. It's the leading cause of disability and the third leading cause of death in women, the researchers said in background notes.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Innovation in robotic rehabilitation technology will provide the first-of-its-kind medical device to rehab clinics nationwide, to treat the millions of patients with lower limb disability due to stroke MARLBOROUGH, Mass. and YOKNEAM ILIT, Israel, Feb. 1... Devices, FDA ReWalk Robotics, exo-suit, stroke
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
The antidepressant fluoxetine works no better than placebo to reduce disability after a stroke, lowering hopes that had been raised by other smaller studies. After a six month trial including more than 3,000 adult stroke patients recruited at 103 UK hospitals, researchers concluded that fluoxetine should not be used to promote recovery from stroke-related disability, or routinely prescribed to prevent depression after stroke. Several smaller studies and animal trials had found promising results from the use of fluoxetine after stroke. However, this trial of fluoxetine 20mg daily for six months found no improvement in funct...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
ConclusionIntramuscular treatment with Cerebrolysin of post-stroke spasticity was safe and effective in this patient. The experiences observed in this patient are in line with the findings of a larger cohort study treated in the same way in the Philippines.
Source: Neurology and Therapy - Category: Neurology Source Type: research
Abstract OBJECTIVEPostoperative neurological deficits impair the overall outcome of revascularization surgery for patients with moyamoya disease (MMD). dl-3-n-butylphthalide (NBP) is approved for the treatment of ischemic stroke in China. This pilot study evaluated the effect of NBP on perioperative stroke and neurological deficits in patients with MMD.METHODSThe authors studied cases in which patients underwent combined revascularization surgery for MMD at their institution, with or without NBP administration. The overall study group included 164 patients (213 surgically treated hemispheres), including 49 patient...
Source: Journal of Neurosurgery - Category: Neurosurgery Authors: Tags: J Neurosurg Source Type: research
CONCLUSION: This case study demonstrated that even in a universal healthcare system, post-stroke participation for those with low incomes was severely restricted. Changes at the clinical level and at the public policy level could facilitate participation. Implications for rehabilitation Income influenced the experience of return to participation for the low-income stroke survivors by limiting their ability to afford housing, goods, and services. The macro environment, which regulates the healthcare and social service systems, was the strongest influence on return to participation for low income stroke survivors. Findings p...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
CONCLUSIONS: We found no evidence to support the use of calcium antagonists in people with acute ischemic stroke. PMID: 30758052 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
AbstractPurposeBCVI may lead to ischemic stroke, disability, and death, while being often initially clinically silent. Screening criteria for BCVI based on clinical findings and trauma mechanism have improved detection, with Denver criteria being most common. Up to 30% of patients do not meet BCVI screening criteria. The aim of this study was to analyze the effect of augmented Denver criteria on detection, and to determine the relative risk for ischemic stroke.MethodsDenver screening criteria were augmented by any high-energy trauma of the cervical spine, thorax, abdomen, or pelvis. All acute blunt trauma WBCT including CT...
Source: Emergency Radiology - Category: Emergency Medicine Source Type: research
Transplanted neural stem cells (NSCs) have demonstrated multimodal therapeutic function after stroke. In preclinical stroke models, NSCs have been shown to modulate inflammation, foster neuroplasticity, and neural reorganization; promote angiogenesis; and act as a cellular replacement by differentiating into mature neural cell types. Understanding the key factors involved in NSC ‐mediated tissue recovery and addressing the current translational barriers may lead to clinical success of NSC therapy and a first‐in‐class restorative therapy for stroke patients. AbstractIntroductionNeural stem cells (NSCs) have demonstrat...
Source: Brain and Behavior - Category: Neurology Authors: Tags: REVIEW Source Type: research
AbstractStroke is one of the leading causes of long-term disability. Cell transplantation is a promising strategy to treat stroke. We explored the efficacy of directly reprogrammed human neural precursor cell (drNPC) transplants to promote functional recovery in a model of focal ischemic stroke in the mouse sensorimotor cortex. We show that drNPCs express neural precursor cell markers and are neurally committed at the time of transplantation. Mice that received drNPC transplants recovered motor function, irrespective of transplant vehicle or recipient sex, and with no correlation to lesion volume or glial scarring. The maj...
Source: Translational Stroke Research - Category: Neurology Source Type: research
Semin Neurol 2019; 39: 061-072 DOI: 10.1055/s-0038-1676992Stroke remains one of the leading determinants of death and severe disability worldwide. It is a medical emergency with a narrow window for recognition and administration of outcome-modifying treatment in the emergency department. Ischemic stroke accounts for the majority of cerebrovascular events and revascularization therapies such as intravenous thrombolysis and endovascular thrombectomy are the mainstays of treatment in carefully selected patients. Intracerebral hemorrhage is less common but remains the deadliest type of stroke. Blood pressure reduction and hemo...
Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
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