[Correspondence] Great expectations – Authors’ reply

Non-ST-segment elevation myocardial infarction (NSTEMI) is associated with relevant mid-term mortality and might be associated with poorer long-term prognosis compared with ST-segment elevation myocardial infarction.1 All-cause mortality is the most objective and clinically meaningful endpoint regarding data quality of randomised controlled trials and patient prognosis. However, as pointed out by Gilles Lemesle and colleagues, all-cause mortality is unlikely to be an appropriate endpoint to power a randomised controlled trial funded by a government agency and investigating the optimal timing of invasive coronary angiography or other treatment strategies in non-ST-segment elevation acute coronary syndromes (NSTE-ACS).
Source: LANCET - Category: General Medicine Authors: Tags: Correspondence Source Type: research