PRN Ranibizumab in the Treatment of Choroidal Neovascularization Secondary to Ocular Histoplasmosis

Ocular histoplasmosis syndrome (OHS) is a systemic disease thought to be caused by the inhalation and systemic spread of the dimorphic fungal organism Histoplasma capsulatum. A mild systemic infection occurs after the initial infection and results in granulomatous inflammation and resultant encapsulation primarily in the lungs and the choroid. The classic ocular findings for OHS include peripheral chorioretinal scarring ( “histo spots”), peripapillary atrophy and hyperplasia, and maculopathy (or choroidal neovascularization [CNV]). The development of CNV is the primary ocular complication

Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Edward H. Wood, MD Source Type: research