Diastereo- and enantioselective nitro-Mannich reaction of isatin-derived N-Boc ketimines catalyzed by chiral phase-transfer catalysts

New J. Chem., 2018, Advance Article DOI: 10.1039/C7NJ04527A, LetterYuxin Liu, Jingdong Wang, Zhonglin Wei, Jungang Cao, Dapeng Liang, Yingjie Lin, Haifeng Duan A series of 3-substituted 3-amino-oxindoles were constructed in excellent yields (96-99%) with high enantioselectivities (up to 95% ee) and diastereoselectivities (up to 95 : 5 dr) catalyzed by Cinchona alkaloid-derived phase-transfer catalysts. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - New J. Chem. latest articles - January 17, 2018 Category: Chemistry Authors: Yuxin Liu Source Type: research