Final USPSTF Rec: Don't Use HRT to Prevent Chronic Illness Final USPSTF Rec: Don't Use HRT to Prevent Chronic Illness

The US Preventive Services Task Force's final recommendation follows its previous guidance from 2012. Hormone replacement therapy has benefits, members say, but also well-documented harms.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

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In this study we aimed to evaluate the efficacy of Pycnogenol® supplementation in controlling oxidative stress levels and in reducing the frequency and severity of side effects of levothyroxine (LT4) treatment in patients who had recently started this therapy. METHODS: The registry included 60 females affected by primary hypothyroidism with multi-nodular goiter. LT4 was administered at the dosage of 100 μg/day.The registry study included only subjects under initial treatment, and followed up for a period of at least 30 days. A group took 150 mg Pycnogenol® daily and another served as control. RESULTS: Th...
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Abstract PURPOSE OF REVIEW: Optimizing the management of deceased organ donors focuses on providing critical care that prevents, mitigates, or repairs the pathophysiologic sequelae of brain death. This review discusses protocol-based care; approaches to monitoring, resuscitation, hormone replacement therapy, and respiratory management; and the potential of various additional donor therapies. RECENT FINDINGS: Protocol-based critical care after the determination of brain death has the potential to substantially increase the quantity and improve the quality of organs available for transplantation. Close hemodyna...
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Tags: Curr Opin Organ Transplant Source Type: research
Purpose of review Optimizing the management of deceased organ donors focuses on providing critical care that prevents, mitigates, or repairs the pathophysiologic sequelae of brain death. This review discusses protocol-based care; approaches to monitoring, resuscitation, hormone replacement therapy, and respiratory management; and the potential of various additional donor therapies. Recent findings Protocol-based critical care after the determination of brain death has the potential to substantially increase the quantity and improve the quality of organs available for transplantation. Close hemodynamic monitoring with ...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: ETHICAL CONSIDERATIONS OF ALLOCATION: Edited by David A. Axelrod Source Type: research
A study published in theBMJhas suggested that transgender women are at a greater risk of developing breast cancer after hormone replacement therapy.Daily Mail
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Since the Women's Health Initiative (WHI) has been stopped 2002 due to increased risk of venous thromboembolism, myocardial infarction, stroke and breast cancer, safety issues have got great concern using hormone replacement therapy (HRT). However, using lower dosages, other hormonal components and/or transdermal instead of oral application can reduce those risks although not demonstrated in a placebo-controlled study comparable to WHI. However, this has been shown in large case/control- and cohort-studies reflecting more practical conditions in contrast to WHI.
Source: Maturitas - Category: Primary Care Authors: Tags: INV65 Source Type: research
With the publication of adverse effects of a hormone replacement therapy in 2002 the wish of many women for a more natural and safer treatment method increased rapidly. Soy, soy preparations and black cohosh/cimicifuga racemosa became the most popular herbal remedies for the relief of hot flushes. Until today only a few randomised trials were published about herbal medicine. The results regarding efficacy and safety are still conflicting, although in recent years more promising outcomes have emerged.
Source: Maturitas - Category: Primary Care Authors: Tags: INV59 Source Type: research
Premature ovarian insufficiency (POI) is a condition characterized by sex-steroid deficiency, amenorrhea, infertility and elevated gonadotropins in women younger than 40 years of age. Women with POI need exogenous sex steroids to compensate for the decreased production by their ovaries and for these young women hormone replacement therapy is “true replacement” of ovarian hormones. Optimal hormone therapy depends on whether the patient has primary or secondary amenorrhea. Young women with primary amenorrhea in whom secondary sex characteristics have failed to develop initially should be given very low doses of e...
Source: Maturitas - Category: Primary Care Authors: Tags: INV48 Source Type: research
is a major component of health and well-being, although it is often neglected by both patients and health care providers. Sexual dysfunction appears early after menopause due to both vaginal dryness/dyspareunia and decreased libido, as an effect of hypoestrogenism in the periphery as well as in the central nervous system. Systemic (hormone replacement therapy) and topical estrogens (in the form of vaginal creams/gels) represent the main available therapeutic interventions.
Source: Maturitas - Category: Primary Care Authors: Tags: INV47 Source Type: research
To this discuss this topic the meaning of “natural” in hormone replacement therapy (HRT) needs to be defined. What is “natural” to the women that seek advice from their gynecologist? Biological products, derived directly from nature, are in general associated with fewer side effects, low or even no risks, but is this feeling evidenc e based? To advice our patients based on actual knowledge these issues are thoroughly reviewed and compared to synthetic treatment options with regard to breast cancer, endometrial cancer, cardiovascular events, diabetes and others.
Source: Maturitas - Category: Primary Care Authors: Tags: P76 Source Type: research
Objectives: Women experience varying physical and psychological symptoms as they transit through post-reproducitve phase of life or Menopause. The commonly recommended Hormone Replacement Therapy (HRT)2 is losing its popularity among midlife women due to associated risks and side-effects. Hence the objective of this study was to develop and investigate the effect of a Complementary Alternative Medicine (CAM)3, which was holistic in nature.
Source: Maturitas - Category: Primary Care Authors: Tags: P05 Source Type: research
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