Final USPSTF Rec: Don't Use HRT to Prevent Chronic Illness Final USPSTF Rec: Don't Use HRT to Prevent Chronic Illness

The US Preventive Services Task Force's final recommendation follows its previous guidance from 2012. Hormone replacement therapy has benefits, members say, but also well-documented harms.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Related Links:

(MedPage Today) -- Drop in risk occurred regardless of menopausal status or hormone replacement therapy
Source: MedPage Today Cardiovascular - Category: Cardiology Source Type: news
AbstractPatient-reported outcomes (PROs) provide practical guides for treatment; however, studies that have evaluated PROs of women in Korea with postmenopausal osteoporosis (PMO) are lacking. This cross-sectional, multi-center (29 nationwide hospitals) study, performed from March 2013 to July 2014, aimed to assess PROs related to treatment satisfaction, medication adherence, and quality of life (QoL) in Korean PMO women using osteoporosis medication for prevention/treatment. Patient demographics, clinical characteristics, treatment patterns, PROs, and experience using medication were collected. The 14-item Treatment Satis...
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research
Abstract Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. The effect of estrogen on these diseases has been assessed in in vitro and in vivo models, as well as in observational studies. Collectively, these studies alluded to a cardiovasculo-protective effect of estrogen. However, comprehensive clinical investigation failed to produce concrete proof of a cardiovascular protective effect for hormone replacement therapy (HRT), let alone rule out potential harm. These seemingly paradoxical effects of estrogen were explained by the 'theory of timing and opportunity'. This theory states...
Source: Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Vascul Pharmacol Source Type: research
AbstractPurposeTo evaluate the effectiveness of ovarian transposition (OT) prior to radiation therapy (RT) and to evaluate the effect of age on ovarian survival (OS) after OT.MethodsWe performed a retrospective control study, with women (aged    40 IU/L and/or estradiol 
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionsWVI or WBRT+  primary boost (PB) is a sufficient irradiation field for localized intracranial germinoma, while patients with bifocal disease should undergo craniospinal irradiation (CSI), especially when treated with RT alone. CSF β-HCG is not a prognostic marker for intracranial germinomas. The treatment res ults of chemotherapy followed by reduced-dose RT are comparable to those of RT alone. IMRT is recommended for intracranial germinoma to improve the target volume accuracy and decrease the complications of RT.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
In conclusion, HSC ageing is characterised by reduced self-renewal, myeloid and platelet HSC skewing, and expanded clonal haematopoiesis that is considered a preleukaemic state. The underlying molecular mechanisms seem to be related to increased oxidative stress due to ROS accumulation and DNA damage, which are influenced by both cell- and cell non-autonomous mechanisms such as prolonged exposure to infections, inflammageing, immunosenescence, and age-related changes in the HSC niche. Thus, HSC ageing seems to be multifactorial and we are only beginning to connect all the dots. The Price of Progress or the Waste...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Sex Differences in the Vascular Function and Related Mechanisms: Role of 17βEstradiol. Am J Physiol Heart Circ Physiol. 2018 Sep 07;: Authors: Pabbidi MR, Kuppusamy M, Didion SP, Sanapureddy P, Reed J, Sontakke SP Abstract The incidence of cardiovascular disease (CVD) is lower in pre-menopausal women but increases with age and menopause compared to similar-aged men. Based on the prevalence of CVD in the post-menopausal women, sex hormone-dependent mechanisms have been postulated to be the primary factors responsible for the protection from CVD in pre-menopausal women. Recent Women's Health Initia...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research
This popular science article covers some of the major research topics related to sarcopenia, the loss of muscle mass and strength that occurs with age. A great deal is known of the biochemistry of muscle aging, the signals and mechanisms involved in muscle stem cell activity and muscle growth, and how they change with age. A great deal more remains to be discovered, and fitting together what is already known into a coherent whole is a still a work in progress. Any proposed layering of cause and effect is speculative at best, and it is usually unclear as to where exactly any newly described signal or mechanism fits. It it i...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Ever since a report by a U.S. study claimed in 2002 that it carried a significant risk of breast cancer and heart disease, most menopausal women remain scared of taking it.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionLower LDL-C levels were significantly associated with lower free T and lower FAI in a general population of men. Moreover, both low and high levels of LDL-C might be risk factors for ED.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
More News: Health | Hormone Replacement Therapy | Hormones | Women