Your NEJM Group Today: Hepatitis A Outbreak / Low Accuracy of Clinician Suspicion for Lyme Disease / Connecticut Hospitalist Opportunity

Check out some of the recent highlights from NEJM Group: NEJM: Perspective: Dr. Margot Kushel examines the root cause of a hepatitis A outbreak in...
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news

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The objective of this study was to determine the epidemiological characteristics of leptospirosis in pets and in humans in peridomestic settings in Nicaragua between 2014 and 2016. Methods: The samples were taken in areas where cases were confirmed in humans using non-probabilistic sampling in 10 of the country's 17 departments. This included 112 urine samples from pets, 129 water samples, and 69 soil samples in order to isolate leptospires in Ellinghausen-McCullough-Johnson-Harris (EMJH) medium. Furthermore, the microscopic agglutination test (MAT) was applied to 263 samples of animal serum, and 88 isolates were analy...
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
amune Reactivation of hepatitis B virus (HBV) is a major problem in patients receiving chemotherapy for malignant diseases or immunosuppression therapies. It has been thought that a reduction in the immune responses might result in the reactivation of HBV replication from covalently closed circular DNA (cccDNA) residing in hepatocytes. However, not only the host’s immune status, but also viral mutations have been reported to be associated with reactivation. Especially, several case reports about amino acid mutations in hepatitis B surface antigen (HBsAg) that escape from immune reactions have been reported, a...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Authors: Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, endorsed by scientific societies Abstract Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevent...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
ConclusionsHand hygiene and an intensive isolation strategy remained the most critical precautions for preventing an outbreak of healthcare-associated viral gastroenteritis in the neonate care unit.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
ConclusionsTelaprevir is more effective and cost-effective than boceprevir. Our model may be applied for other settings with a few adjustments in the input parameters.
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
Conclusions:Although women do not constitute a signifcant part of substance abuse, increasing trend of women addiction, on one hand, and high prevalence of risk factors related to HIV or hepatitis in women, on the other hand; show that offcials and experts are required to seriously consider prevention and harm reduction programs for women.Keywords:Addicted women, addictive, behavior, methadone maintenance treatment, methadone,substance abuse, substance ‑related disorders
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 16 May 2019Source: CellAuthor(s): Carl W. Davis, Katherine J.L. Jackson, Anita K. McElroy, Peter Halfmann, Jessica Huang, Chakravarthy Chennareddy, Ashley E. Piper, Yvonne Leung, César G. Albariño, Ian Crozier, Ali H. Ellebedy, John Sidney, Alessandro Sette, Tianwei Yu, Sandra C.A. Nielsen, Arthur J. Goff, Christina F. Spiropoulou, Erica Ollman Saphire, Guy Cavet, Yoshihiro KawaokaSummaryEbola virus (EBOV) remains a public health threat. We performed a longitudinal study of B cell responses to EBOV in four survivors of the 2014 West African outbreak. Infection induced lastin...
Source: Cell - Category: Cytology Source Type: research
ROCKPORT (CBS) – Officials at the Massachusetts Department of Public Health are warning customers of Ray Moore’s Fish Shack in Rockport that they may have been exposed to hepatitis A. An employee who worked at the restaurant from April 21-May 12 has been diagnosed with hepatitis A. Customers who dined during that time on cold or uncooked items such as salad, breads (including rolls and hot dog and hamburger buns), cold desserts, fruit or vegetable garnishes, condiments such as pickles and onions, chips and beverages containing ice should contact a doctor to receive treatment for possible exposure to hepatitis A...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated Local Hepatitis A Rockport News Source Type: news
This study aimed to improve the detection methods for Sarcocystis, in order to have a clearer picture of the true diversity of Sarcocystis species in Tioman. A new primer set (28S R7F-28S R8 Deg R) was designed to amplify the 28S rRNA gene of Sarcocystis. Subsequently, Sarcocystidae was detected in 65.6% (21/32) of water samples and 28% (7/25) of soil samples acquired between 2014 and 2015 from Tioman. Next-generation sequencing (NGS) on 18 of the positive samples was then performed using amplicons generated from the same primer set. This yielded 53 potentially unique Sarcocystidae sequences (290 bp), of which nine of the ...
Source: Journal of Water and Health - Category: Environmental Health Tags: J Water Health Source Type: research
Authors: Wood M, Simmonds L, MacAdam J, Hassard F, Jarvis P, Chalmers RM Abstract Most commercial swimming pools use pressurised filters, typically containing sand media, to remove suspended solids as part of the water treatment process designed to keep water attractive, clean and safe. The accidental release of faecal material by bathers presents a poorly quantified risk to the safety of swimmers using the pool. The water treatment process usually includes a combination of maintaining a residual concentration of an appropriate biocide in the pool together with filtration to physically remove particles, including m...
Source: Journal of Water and Health - Category: Environmental Health Tags: J Water Health Source Type: research
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