Effect of sedation on quantitative electroencephalography after cardiac arrest

Electroencephalography (EEG) has clinical and prognostic importance after cardiac arrest (CA). Recently, interest in quantitative EEG (qEEG) analysis has grown. The qualitative effects of sedation on EEG are well known, but potentially confounding effects of sedatives on qEEG after anoxic injury are poorly characterized. We hypothesize that sedation increases suppression ratio (SR) and decreases alpha/delta ratio (ADR) and amplitude-integrated EEG (aEEG), and that the magnitude of sedation effects will be associated with outcome.

Source: Resuscitation - November 29, 2017 Category: Emergency Medicine Authors: Callie M. Drohan, Alessandra I. Cardi, Jon C. Rittenberger, Alexandra Popescu, Clifton W. Callaway, Maria E. Baldwin, Jonathan Elmer Tags: Clinical paper Source Type: research