There's a hospital ship waiting for sick Puerto Ricans -- but no one knows how to get on it
Sammy Rolon is living in a makeshift clinic set up at a school. He has cerebral palsy and epilepsy and is bedridden. He's waiting for surgery that was scheduled before Hurricane Maria smashed into Puerto Rico. Now, he can't even get the oxygen he needs.
Neonatal seizures occur in 1.5 –3.5 per 1000 term live births, with a higher incidence (10–130 per 1000) in preterm live births. They often remain undiagnosed, accurate diagnosis is highly dependent upon clinical expertise and the availability of monitoring equipment. There is a strong association between neonatal seizures an d adverse neurodevelopmental outcome. Up to 50% of infants with seizures will go on to have some form of long term neurological sequelae, e.g. epilepsy, cerebral palsy, and/or intellectual disability.
CONCLUSIONS: Our results show that a diagnosis of confirmed isolated mild ventriculomegaly was associated with an increased risk of neurodevelopmental disorders compared to the reference population, but the absolute risk was low and there were no cases of intellectual disability or cerebral palsy. This article is protected by copyright. All rights reserved. PMID: 30168217 [PubMed - as supplied by publisher]
ConclusionsThe long-term quality of life after paediatric intensive care is good for the majority of children and young people, and it is dependent on the number of chronic diagnoses and the burden of the chronic disease, especially neurological diseases.
Perinatal arterial ischaemic stroke (PAIS) affects between 1:2300 and 1:4000 births, so most paediatricians and neonatologists will see a number of cases during their working life. The exact cause of PAIS in an individual usually is unknown, and discussion may occur about whether prothrombotic investigations, aspirin or anticoagulation are needed. The causes, investigation and treatment of PAIS are completely different from stroke in the older paediatric and adult group. Outcome tends to be good, although cerebral palsy may be seen in up to 30% of cases, epilepsy in 15 –25% and cognitive problems may also occur.
Publication date: Available online 10 August 2018Source: Neurotoxicology and TeratologyAuthor(s): Takashi Yorifuji, Shigeru Takaoka, Philippe GrandjeanAbstractSevere methylmercury poisoning occurred in Minamata and neighboring communities in Japan during the 1950s and 1960s. A considerable number of children were born with conditions resembling cerebral palsy, later known as congenital Minamata disease. Although surviving patients are now in their 50s or 60s, few assessments of functional capacities in daily living have been performed. We assessed the changes in Activities of Daily Living (ADL) status of 11 patients over a...
CONCLUSIONS: The use of population registers allows a better knowledge of cerebral palsy as well as the evaluation and development of prevention strategies and optimization of care resources with objective data. It is necessary to generalize the use of this type of records in our environment. PMID: 30047119 [PubMed - in process]
Noise levels exceed WHO recommendations and impact on sleep of children and their parents Related items fromOnMedica Cerebral palsy risk linked to low Apgar Adherence to medicine schedule – low among children with epilepsy Child health should be election priority say experts and public UK lagging behind peers on child health Government launches its Child Health Strategy
Publication date: 2018Source: NeuroImage: Clinical, Volume 20Author(s): Sabrina Yu, Helen L. Carlson, Aleksandra Mineyko, Brian L. Brooks, Andrea Kuczynski, Jacquie Hodge, Sean Dukelow, Adam KirtonAbstractBackgroundStroke is a leading cause of perinatal brain injury with variable outcomes including cerebral palsy and epilepsy. The biological processes that underlie these heterogeneous outcomes are poorly understood. Alterations in developmental myelination are recognized as a major determinant of outcome in preterm brain injury but have not been explored in perinatal stroke. We aimed to characterize myelination in hemipare...
Conclusions and ImplicationsThe results of this analysis suggest that while children diagnosed with CP and with access to stored CB differ from a broader population sample in terms of demographics, they have similar clinical severity and comorbidity profiles. As such, LUSTRE may serve as a valuable source of data for the characterization of individuals with CP, including individuals who have or will receive CB infusions.
Abstract Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children's neurodevelopment. We discuss the potential mechanisms by which inflammatory molecules can exert their effects on the developing brain and consider the roles of MHC class I molecules, the HPA axis, glial cells, and monoamine metabolism. Methods to prevent the effects of cytokine imbalance may lead t...