The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

Nature Immunology 15, 727 (2014).
doi:10.1038/ni.2913

Authors: Bernardo S Franklin, Lukas Bossaller, Dominic De Nardo, Jacqueline M Ratter, Andrea Stutz, Gudrun Engels, Christoph Brenker, Mark Nordhoff, Sandra R Mirandola, Ashraf Al-Amoudi, Matthew S Mangan, Sebastian Zimmer, Brian G Monks, Martin Fricke, Reinhold E Schmidt, Terje Espevik, Bernadette Jones, Andrew G Jarnicki, Philip M Hansbro, Patricia Busto, Ann Marshak-Rothstein, Simone Hornemann, Adriano Aguzzi, Wolfgang Kastenmüller & Eicke Latz

Source: Nature Immunology - June 22, 2014 Category: Allergy & Immunology Authors: Bernardo S FranklinLukas BossallerDominic De NardoJacqueline M RatterAndrea StutzGudrun EngelsChristoph BrenkerMark NordhoffSandra R MirandolaAshraf Al-AmoudiMatthew S ManganSebastian ZimmerBrian G MonksMartin FrickeReinhold E SchmidtTerje EspevikBernadet Tags: Article Source Type: research