The role of A-kinase anchoring protein 95-like protein in annealing of tRNALys3 to HIV-1 RNA

Conclusion:
The results support a hypothesis that HAP95 may transiently block RHA's activity to protect the annealed tRNALys3 on viral RNA in the cells from removing by RHA during the packaging of RHA into virus particles, thus facilitating the annealing of tRNALys3 to HIV-1 RNA.

Source: Epidemiologic Perspectives and Innovations - July 17, 2014 Category: Epidemiology Authors: Li XingXia ZhaoFei GuoLawrence Kleiman Source Type: research