Systematic review of interventions for treating or preventing antipsychotic-induced tardive dyskinesia

Antipsychotic medication can cause tardive dyskinesia (TD) – late-onset, involuntary, repetitive movements, often involving the face and tongue. TD occurs in> 20% of adults taking antipsychotic medication (first-generation antipsychotics for> 3 months), with this proportion increasing by 5% per year among those who continue to use these drugs. The incidence of TD among those taking newer antipsychotics is not different from the rate in people who have used older-generation drugs in moderate doses. Studies of TD have previously been found to be limited, with no treatment approach shown to be effective.

To summarise the clinical effectiveness and safety of treatments for TD by updating past Cochrane reviews with new evidence and improved methods; to undertake public consultation to gauge the importance of the topic for people living with TD/the risk of TD; and to make available all data from rele vant trials.

Source: Current Awareness Service for Health (CASH) - September 25, 2017 Category: Consumer Health News Source Type: news