Medical News Today: Asthma and ibuprofen: What are the effects?

Medicines can often interact with pre-existing conditions. In this article, we look at the effects of ibuprofen in people with asthma.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

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Authors: Srisingh K, Weerakul J, Srijuntongsiri S, Ngoenmak T Abstract Objective: To identify risk factors which may lead to the occurrence of recurrent wheezing in children under five years of age. Material and Method: A cross-sectional study was conducted in children under 5 years old at the Out Patient Department at Naresuan University Hospital, from October 2013 to October 2014. Fifty-five children who had signs and symptoms of recurrent wheezing were assigned to the study group, whereas another fifty-five children matching on age and sex with the case who had no symptoms of recurrent wheezing were assigned...
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: General Medicine Tags: J Med Assoc Thai Source Type: research
At the end of a quiet and unassuming neighborhood street in Pontiac, Michigan, a red-brick church stands forlorn. No sign indicates whether the tired building continues to hold Sunday-morning services; however, it respectfully stands erect. It’s here that I met Misa Mi on a warm October morning last fall. As the Director of Curriculum Evaluation and Associate Professor of Biomedical Sciences at Oakland University William Beaumont School of Medicine, as well as the school’s health information specialist, she received a GMR grant in 2016 to fund a health literacy project for the HOPE Recuperative Care Center, a n...
Source: The Cornflower - Category: Databases & Libraries Authors: Tags: Blog Consumer Health Funding News from the Region Outreach Success Stories Source Type: news
Johnson &Johnson (NYSE:JNJ) opened its latest life science incubator in New York City, the healthcare giant said today. The 30,000-square-foot JLabs @ NYC is a collaboration between Johnson &Johnson Innovation, New York State and the New York Genome Center. Sited at the genome center in SoHo, the incubator is home to 26 startups and has room for four more, New Brunswick, N.J.-based J&J said. “Johnson &Johnson has deep entrepreneurial roots in New York and we are pleased to see our unique JLabs model applied in this rich ecosystem to foster the creation of new healthcare innovations that have the pote...
Source: Mass Device - Category: Medical Devices Authors: Tags: Funding Roundup Research & Development johnsonandjohnson Source Type: news
(CBS Local)- Former Surgeon General Doctor Vivek Murthy brought mental health to the forefront last September when he wrote in the Harvard Business Review that loneliness is a “growing health epidemic.” Now a recent survey by health service company Cigna adds to that by showing many Americans say they sometimes or always feel alone. The survey of more than 20,000 U.S. adults ages 18 years and older revealed some alarming findings: Nearly half of Americans report sometimes or always feeling alone (46 percent) or left out (47 percent). One in four Americans (27 percent) rarely or never f...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Local TV Mental Health talkers Source Type: news
Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice. Mol Med Rep. 2018 Jun 18;: Authors: Shan L, Kang X, Liu F, Cai X, Han X, Shang Y Abstract The present study aimed to investigate the effect of epigallocatechin gallate (EGCG) on airway inflammation in mice with bronchial asthma, and the regulatory mechanism of transforming growth factor (TGF)‑β1 signaling pathway, so as to provide theoretical basis for research and development of a novel drug for clinical treatment. Mouse models of bronchial asthma were established and injected with d...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Montelukast inhibits RANKL‑induced osteoclast formation and bone loss via CysLTR1 and P2Y12. Mol Med Rep. 2018 Jun 15;: Authors: Kang JH, Lim H, Lee DS, Yim M Abstract Osteoclasts (OCs) are resorptive cells responsible for bone erosion in diseases, including osteoporosis, periodontitis and rheumatoid arthritis. Montelukast is a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist clinically used for the treatment of asthma. In the present study, the role of CysLTR1 on OC formation and bone loss was investigated using montelukast. Montelukast inhibited receptor activator of nuclear factor‑κB ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Selene Baos, David Calzada, Luc ía Cremades-Jimeno, Joaquín Sastre, César Picado, Joaquín Quiralte, Fernando Florido, Carlos Lahoz, Blanca Cárdaba
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
(American College of Allergy, Asthma, and Immunology) A new study shows in an emergency, 52 percent of adults with potentially life-threatening allergies didn't use the epinephrine auto-injectors (EAI) they were prescribed.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Chitin is a polysaccharide that provides structure and rigidity to the cell walls of fungi and insects. Mammals possess multiple chitinases, which function to degrade chitin, thereby supporting a role for chitinases in immune defense. However, chitin degradation has been implicated in the pathogenesis of asthma. Here, we determined the impact of acidic mammalian chitinase (AMCase) (Chia) deficiency on host defense during acute exposure to the fungal pathogen Aspergillus fumigatus as well as its contribution to A. fumigatus-associated allergic asthma. We demonstrate that chitin in the fungal cell wall was detected at low le...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Host Response and Inflammation Source Type: research
Both asthma and rhinosinusitis are complex and heterogeneous diseases and, importantly, they often coexist: these diseases can be concomitant in 35 –65% of affected children, according to different studies. Thus, evaluating this comorbidity in the clinical practice should be paramount. In this review, we focused our discussion on the multiple pathophysiological aspects that may link rhinosinusitis and asthma in the pediatric population. Altho ugh rhinosinusitis may exacerbate asthma through several mechanisms occurring by contiguity, actually this aspect seems to be only one component of the complex interplay between...
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Tags: Short review Source Type: research
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