Surveillance for highly pathogenic influenza A viruses in California during 2014 –2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway

Surveillance for highly pathogenic influenza A viruses in California during 2014–2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway Emerging Microbes &Infections 6, e80 (September 2017). doi:10.1038/emi.2017.66 Authors: Andrew M Ramey, Nichola J Hill, Troy Cline, Magdalena Plancarte, Susan De La Cruz, Michael L Casazza, Joshua T Ackerman, Joseph P Fleskes, T Winston Vickers, Andrew B Reeves, Frances Gulland, Christine Fontaine, Diann J Prosser, Jonathan A Runstadler &Walter M Boyce
Source: Emerging Microbes and Infections - Category: Infectious Diseases Authors: Tags: California clade 2.3.4.4 H5 highly pathogenic influenza A pinniped virus waterfowl Source Type: research

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AbstractThe etiologies of undifferentiated fever in pregnant women have not been studied thoroughly. Because of its non-specific presentation but severe prognosis, listeriosis is often suspected in this setting, but in most cases not confirmed. We studied the causes of undifferentiated fever in pregnant women who received preemptive listeriosis treatment. We conducted from November 1, 2011, to June 30, 2013, a prospective multicentric observational cohort study of pregnant women referred to obstetrical wards with undifferentiated fever and who received listeriosis preemptive treatment. Clinical and biological features, tre...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): S. Al Katy, J.P. Stewart, A. Kipar
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): C. Bianco, A. Nunez, P. Sanchez-Cordon, R. Hansen, S. Reid, S. Jeckel, I.H. Brown, S. Thomas, C. Poulos, S.M. Brooks
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): S.A. Bergervoet, S. Vreman, R. Zwart, N. Stockhofe-Zurwieden, N. Beerens
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
Abstract Multiple genetically distinct influenza B/Victoria lineage viruses have cocirculated in the United States recently, circulating sporadically during the 2018-19 season and more frequently early during the 2019-20 season (1). The beginning of the 2019-20 influenza season in Louisiana was unusually early and intense, with infections primarily caused by influenza B/Victoria lineage viruses. One large pediatric health care facility in New Orleans (facility A) reported 1,268 laboratory-confirmed influenza B virus infections, including 23 hospitalizations from July 31 to November 21, 2019, a time when influenza ...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a potential diagnostic test for pneumococcal pneumonia. We enrolled 348 children with pneumonia admitted to Patan Hospital, Kathmandu, Nepal between December 2015 and September 2016. PBMCs sampled from participants were incubated for 48 h before harvesting of cell culture supernatant (ALS). We used a fluorescence-based multiplexed immunoassay to measure the concentration of IgG in A...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect. Here we analyzed distribution of a highly polymorphous HLA-DRB1 locus in more than one thousand relapsing-remitting MS patients and healthy individuals of Russian ethnicity. Carriage of HLA-DRB1*15 and HLA-DRB1*03 alleles was associated with MS risk, whereas carriage of HLA-DRB1*01 and HLA-DRB1*11 was found to be protective. Analysis of genotypes revealed the compensatory effect of risk and resistance alleles in trans....
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
chi Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs. It is necessary to understand the detailed and complex interactions between influenza virus and its host cells in order to identify successful strategies for therapeutic intervention. During viral entry, the cellular microenvironment presents invading pathogens with a series of obstacles that must be overcome to infect permissive cells. Influenza hijacks numerous host cell proteins and associated biological pathways during its journey into the cell, respon...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Recently, several reports in the  Journal of Infection have demonstrated the codon usage bias of influenza virus.1–3 Equine influenza (EI) is a severe and highly contagious disease in horses. Equine influenza virus (EIV) is the antigen that causes this important horse disease.4 The prevalent subtype of the virus is H3N8.5 To our knowledge, an evolutionary analysis of codon usage bias of H3N8 EIV has not been investigated. HA and NA are its main surface proteins, responsible for binding the virus to the cell and releasing progeny virus respectively.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
The CDC recently released a Health Alert Network advisory to notify physicians that influenza activity nationally remains high, primarily due to heightened circulation of influenza B/Victoria viruses.
Source: AAFP News - Category: Primary Care Source Type: news
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