Treatment of Marginal Zone Lymphoma

The margin is a part of the lymphoid follicle, the splenic white pulp or a mucosa associated lymphoid area where antigen influx occurs. Associations of antigen presentation influence the pathogenesis, pathophysiology and treatment of the disease. This is also true of the three major subtypes: nodal, splenic and extra-nodal disease. Autoimmunity, chromosomal translocations and distinct microbial pathogens are all implicated in the pathogenesis of MZL. Patients with known infectious origins should be treated for those specific infections appropriately before consideration of other therapy.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Ariela Noy Source Type: research