Obesity and Depression Are Related -- But How?
(MedPage Today) -- Finding physicians who can address both is a challenge
Publication date: December 2017 Source:Trends in Endocrinology & Metabolism, Volume 28, Issue 12 Author(s): Bharath K. Mani, Jeffrey M. Zigman Ghrelin administration induces food intake and body weight gain. Based on these actions, the ghrelin system was initially proposed as an antiobesity target. Subsequent studies using genetic mouse models have raised doubts about the role of the endogenous ghrelin system in mediating body weight homeostasis or obesity. However, this is not to say that the endogenous ghrelin system is not important metabolically or otherwise. Here we review an emerging concept in which the endogen...
Conclusions Current evidence does not suggest exercise is successful in significantly enhancing psychosocial health in adults with obesity. Limitations associated with the reviewed studies could have biased the results toward a lack of effect. Additional high-quality RCTs are needed to improve evidence-based knowledge.
We describe the prevalence, impact and treatment effects of these comorbidities in the difficult asthma population, emphasizing gaps in the current literature. We examine the associations between individual comorbidities and highlight the potential for comorbidity clusters to exert combined effects on asthma outcomes. We conclude by outlining a pragmatic clinical approach to assess comorbidities in difficult asthma.
Conclusions Identified fall risk factors varied over time, highlighting that falling involves a complex interplay of risk factors in mid-age women.
Conditions: Attention-Deficit / Hyperactivity Disorder; Depression; Obesity Interventions: Behavioral: Bright light therapy; Behavioral: Physical exercise Sponsors: Goethe University; Heidelberg University; Radboud University; Hospital Vall d'Hebron; King's College London Recruiting
What is it about flour, i.e., the starch, bran, and germ of seeds of grass plants, such as modern Triticum species of wheat, that makes them extravagantly fattening? The weight gain effect of modern wheat is so powerful that I call it the perfect obesogen, a food that is perfectly crafted to cause obesity. As a society, we have conducted a massive and inadvertent experiment. Based on the flawed logic that emerged from “white flour is bad, whole grains are good” epidemiological observations (or what I would label “white flour is bad, whole grains are less bad” observations), the American diet, thanks...
This infographic focuses on data pertaining to the health status&determinants of adolescent health, including teenage childbearing, tobacco use, suicide, and obesity.
Conclusions— Dyspnea is a common symptom among patients undergoing CTO PCI and improves significantly with successful PCI. Patients with other potentially noncardiac causes of dyspnea reported less dyspnea improvement after CTO PCI.
ConclusionThe presence of MetS in older adults with depression was associated with greater symptom severity and chronicity of depression, which appears to have accounted for the poorer antidepressant response observed in those with MetS. Additionally, our preliminary finding of an association between higher DBP and poorer antidepressant response bears further examination and replication.
Conditions: Obesity; Depression; Physical Activity; Hypertension; Health Behavior; Subjective Health Intervention: Other: Social capital; Neighborhood environment Sponsor: Queen's University Active, not recruiting