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Foamix commences dosing in Phase III trial for acne drug

Foamix Pharmaceuticals has commenced patient dosing in a Phase III clinical trial (FX2017-22) of its product candidate FMX101 in patients with moderate-to-severe acne.
Source: Drug Development Technology - Category: Pharmaceuticals Source Type: news

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Subcision is a commonly performed procedure for depressed rolling scars of acne.1 Breaking up the fibrotic strands mechanically with a blade or needle leads to neocollagenosis and hematoma formation, resulting in elevation of the depressed scars. However, the excessive mechanical force often leads to trauma to the surrounding tissue, excessive bleeding, and large hematoma formation and fibrosis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Tags: JAAD online Source Type: research
The cutaneous manifestations of obesity and the associated metabolic syndrome (MetS) may present with a wide variety of cutaneous findings, including acanthosis nigricans, acrochordon, cellulitis, psoriasis, hidradenitis suppurativa, acne, and hirsutism. Being aware of such clinical signs and the underlying systemic disorders may facilitate earlier diagnoses, thereby permitting earlier of therapy initiation and prevention of long-term sequelae. In this process, dermatologists are key figures in the early detection of MetS and its clinical manifestations.
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research
Acne vulgaris is an epidemic inflammatory disease of the human sebaceous follicle and represents the most common skin disease affecting about 85% of adolescents in Westernized populations. Acne vulgaris is primarily a disease of wealthy countries and exhibits higher prevalence rates in developed compared with developing countries. No acne has been found in non-Westernized populations still living under Paleolithic dietary conditions constraining hyperglycemic carbohydrates, milk, and dairy products.
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research
The metabolic syndrome (MetS), also termed syndrome X, the deadly quartet, and insulin resistance syndrome, has been of interest for many years; however, there has been a striking increase in the prevalence of MetS over the last few decades, coinciding with the global epidemic of obesity and diabetes mellitus.1,2 MetS is a constellation of several clinical and laboratory findings that have been reported to be associated with numerous medical and dermatologic conditions, such as psoriasis, hidradenitis suppurativa, and acne vulgaris; moreover, the severity of psoriasis is significantly associated with MetS at higher psorias...
Source: Clinics in Dermatology - Category: Dermatology Authors: Tags: Commentary Source Type: research
Vegans who do not get enough protein and vitamin B12, which are nutrients found in animal products, have lower energy and acne. New York dietitians weigh in on how to properly diet.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Dark under-eye circles, acne with excess facial hair, thinning eyebrows and blotchy cheeks could be indicative of a health problem, Dr Susan Taylor explains  on the Megyn Kelly TODAY show.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionsBased on the clinical, histometrical, and histochemical assessment, inspite that most volunteers showed significant improvement after treatment, however, the combined use of dermaroller and TCA 15% was more effective in postacne atrophic scars than the use of dermaroller and PRP or dermaroller only.
Source: Journal of Cosmetic Dermatology - Category: Dermatology Authors: Tags: ORIGINAL CONTRIBUTION Source Type: research
DRY SKIN on the face is a problem often experienced during winter. However, along with eczema, psoriasis and acne it is one of ten skin conditions men and women are risking scarring by using make-up.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Updated Date: Dec 8, 2017 EST
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
AbstractPostinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of PIH include intrinsic skin conditions (e.g., acne and eczema) as well as external insults to the skin, such as burn injuries and dermatologic procedures. PIH more commonly occurs in individuals with darker skin, for whom it is often a source of significant psychological distress. Several therapeutic modalities are available for the treatment of PIH, including topical agents, chemical peels, and energy-based devices. We review the epidemiology, clinical presentation, pathogenesis, and treatment of PIH.
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
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