Invisible dermatoses from the perspective of the dermatopathologist. Original observations and novel concepts.

Invisible dermatoses from the perspective of the dermatopathologist. Original observations and novel concepts.
G Ital Dermatol Venereol. 2017 Jul 26;:
Authors: Tomasini C
Abstract
The phrase 'invisible dermatoses' has been used in two different contexts: 1) Invisible dermatoses to the clinician, i.e., diseases with no significant clinical features, 2) invisible dermatoses to the pathologist. These latter comprise a wide spectrum of entities which present with definite and obvious clinical features, but subtle or hidden histological features and are therefore "invisible" histologically. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. The list of such diseases, originally comprising only few entities, has been gradually expanded over decades and now is a large one. This review focuses on the recently expanded spectrum of such diseases, and offers to the dermatopathologist a strategy for their diagnosis, based mainly on proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.
PMID: 28748686 [PubMed - as supplied by publisher]

Source: Giornale Italiano di Dermatologia e Venereologia - July 29, 2017 Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research