Delta neutrophil index as an early predictor of acute appendicitis and acute complicated appendicitis in adults

This retrospective study aimed to evaluate the ability of the delta neutrophil index (DNI) to predict histologically normal appendicitis preoperatively and to differentiate between simple and complicated appen...
Source: World Journal of Emergency Surgery - Category: Emergency Medicine Authors: Source Type: research

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AbstractBackgroundAcute appendicitis is one of the most common abdominal emergencies. Despite all improvements in diagnostic techniques, there are still ongoing problems as proper diagnosis, misdiagnosis and perforated appendicitis. The aim of this study is to demonstrate the clinical value of IMA in patients with appendicitis and to determine the accurate diagnosis of appendicitis in clinically suspected patients.MethodsPediatric patients with acute abdominal pain who had the Pediatric Appendicitis Score (PAS)  ≥ 7 (n = 109) and a control group of 35 patients were included in this prospectiv...
Source: World Journal of Surgery - Category: Surgery Source Type: research
ConclusionAmong patients with appendicitis, there are relevant risk factors predicting appendiceal tumors, especially age and appendiceal diameter in sonography. But the identified risk factors have a low sensitivity and specificity, so obtaining a confident preoperative diagnosis is challenging.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Due to their fundamentally different biology, archaea are consistently overlooked in conventional microbiome surveys. Using amplicon sequencing, we evaluated methodological set-ups to detect archaea in samples from five different body sites: respiratory tract (nasal cavity), digestive tract (mouth, appendix, and stool) and skin. With optimized protocols, the detection of archaeal ribosomal sequence variants (RSVs) was increased from one (found in currently used, so-called “universal” approach) to 81 RSVs in a representative sample set. The results from this extensive primer-evaluation led to the identification ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
There’s been a lot of good news recently for people who experience migraines. In 2018, the U.S. Food and Drug Administration approved three drugs aimed to prevent migraines from occurring, and, over time, help to make them less frequent and less intense. Treating migraine pain while an attack is underway, however, is a bigger challenge. Triptans are the most popular medications used for this purpose, but they don’t work for everyone. In a study published in the New England Journal of Medicine, researchers report encouraging results with a promising class of oral drugs called gepants, which are meant to be taken...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized embargoed study Headache Migraine Source Type: news
Scientists at the University of Birmingham studied 274 hospitals and found those in the UK have the highest rates of unnecessary appendectomies in which the patient's organ turned out to be healthy.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Wiley) Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. A new BJS study examined whether existing risk prediction models can reliably identify which UK patients with a low risk of appendicitis presenting to hospitals with acute right abdominal pain have appendicitis.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
The need for extended postoperative antibiotics (Abx) for complicated (gangrenous or perforated) appendicitis (CA) remains unclear. We hypothesize that giving ≤24 h of Abx for CA is not inferior to a longer duration in preventing infectious complications after appendectomy.
Source: Journal of Surgical Research - Category: Surgery Authors: Source Type: research
Publication date: Available online 2 December 2019Source: The SurgeonAuthor(s): R.M. O'Connell, S. Abd Elwahab, K. MealyAbstractIntroductionAcute Appendicitis and appendicectomy are common surgical emergencies worldwide. However, there is a lack of published data on the impact of hospital grade, surgeon- and hospital-volumes on patient outcomes following appendicectomy.AimTo establish if hospital grade, hospital-volume, or surgeon-volume impacted patient outcomes following appendicectomy.MethodsUsing the National Quality Assurance and Improvement System (NQAIS) data for all appendicectomies performed in Ireland between Jan...
Source: The Surgeon - Category: Surgery Source Type: research
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis. Br J Surg. 2019 Dec 03;: Authors: RIFT Study Group on behalf of the West Midlands Research Collaborative Abstract BACKGROUND: Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. METHODS: A systematic search was completed to identify...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
AbstractBackgroundWe hypothesized that patients living in rural neighborhoods experience delayed access to surgical services manifesting in increased appendiceal perforation rates in cases of appendicitis.MethodsThis population-based cohort study included adult patients with acute appendicitis in Canada (excluding Quebec) between April 2008 and March 2015. The main outcome of interest was rate of perforation. Predictors of interest included socioeconomic, geographic, and individual predictors of perforation. Spatial analysis was used to analyze spatial clustering of perforation.ResultsWe identified 143,195 patients through...
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
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