Predominance of CD4+ T Cells in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma and Identification of a Subset of Patients With Peripheral B-Cell Lymphopenia.

Conclusions: Overall, our work challenges previous findings that cases of THRLBCL are rich in CD8+ T cells and highlights parallels between THRLBCL and nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). Also, an association of THRLBCL with systemic B-cell lymphopenia has not been previously reported but may represent an underrecognized manifestation.
PMID: 28575178 [PubMed - in process]

Source: American Journal of Clinical Pathology - June 1, 2017 Category: Pathology Authors: Kunder C, Cascio MJ, Bakke A, Venkataraman G, O'Malley DP, Ohgami RS Tags: Am J Clin Pathol Source Type: research