Comparison of three commercial knowledge bases for detection of drug-drug interactions in clinical decision support

Conclusion</strong>: The commercial KBs differ considerably in size and quantity of alerts generated. There is less variability in severity ranking of DDIs than suggested by previous studies. All KBs provide very good coverage of the ONC list. More work is needed to standardize the editorial policies and evidence for inclusion of DDIs to reduce variation among knowledge sources and improve relevance. Some DDIs considered contraindicated in all 3 KBs might be possible candidates to add to the ONC list.</span>
Source: Journal of the American Medical Informatics Association - Category: Information Technology Source Type: research