Peripheral Nerve Schwannoma: A Review of Varying Clinical Presentations and Imaging Findings

A schwannoma or neurilemmoma is a benign, isolated, noninvasive, and encapsulated tumor originating from Schwann cells of the peripheral nerve sheath. The incidence of a schwannoma occurring in the foot and ankle is rare, with prevalence rate of 1% to 10%. Schwannomas have no sex predilection, and they commonly occur in patients in their fourth decade. Malignant transformation of benign schwannoma is unusual; however, it is important to note that malignant variants of schwannomas do exist and account for about 5% to 10% of all soft tissue sarcomas.

Source: Journal of Foot and Ankle Surgery - February 21, 2017 Category: Orthopaedics Authors: Pradeep Albert, Jalpen Patel, Karim Badawy, William Weissinger, Marc Brenner, Ian Bourhill, John Parnell Tags: Case Reports and Series Source Type: research