Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies
BackgroundThere is still an urgent clinical need to develop non-invasive diagnostic tests for early ischemic heart disease because, once angina occurs, it is too late. Hypocapnia has long been known to cause coronary artery vasoconstriction. Some new cardiology tests are accompanied by the claim that they must have potential diagnostic value if hypocapnia enhances their cardiac effects in healthy subjects. But no previous study has tested whether hypocapnia produces bigger cardiac effects in patients with angina than in healthy subjects.MethodsSevere hypocapnia (a PetCO2 level of 20 mmHg) lasting>15 min was mechanically...
CONCLUSIONS: OFR had an excellent agreement with FFR in consecutive patients with coronary artery disease. OFR was superior than QFR, and much better than conventional morphological parameters in determining physiological significance of coronary stenosis. The diagnostic performance of OFR was not influenced by presence of prior myocardial infarction or implanted stents. PMID: 31951207 [PubMed - as supplied by publisher]
CONCLUSIONS: Age and female gender are associated with lower CFR, and age with worse CFC in an angiographically non-obstructed coronary artery. CFC seems to be less sensitive to variations in clinical and hemodynamic parameters than CFR, and therefore is a promising tool in contemporary clinical decision making in the cardiac catheterization laboratory. PMID: 31951205 [PubMed - as supplied by publisher]
This study sought to derive and validate a systematic method enabling AVC quantification using computed tomography angiography (CTA) in patients with AS.Methods134 consecutive patients with AS who underwent both NCCT and CTA were included in the study and sub-divided into derivation (n=71) and validation cohorts (n=63). On NCCT, AVC was quantified using Agatston method utilizing the software developed for semi-automatic assessment of coronary calcium. On CTA, mean contrast attenuation of aorta (AortaHU) and standard deviation (SD) was measured in the region-of-interest at level of sinotubular junction.ResultsUsing an adjus...
Conclusion: Vortex obstruction and choroidal vein dilatation were observed in a VKH patient with choroidal detachment, which might be related to its pathophysiology. PMID: 31951785 [PubMed - as supplied by publisher]
Conclusion: DCP ischemia may improve after aflibercept treatment. Central macular vessel density was found to decrease post-treatment, but the clinical relevance needs further investigation. PMID: 31951761 [PubMed - as supplied by publisher]
Publication date: Available online 17 January 2020Source: American Heart JournalAuthor(s): Caroline Hauw-Berlemont, Lionel Lamhaut, Jean-Luc Diehl, Christophe Andreotti, Olivier Varenne, Pierre Leroux, Jean-Baptiste Lascarrou, Patrice Guerin, Thomas Loeb, Eric Roupie, Cédric Daubin, Farzin Beygui, Sophie Glippa, Juliette Djadi-Prat, Gilles Chatellier, Alain Cariou, Christian Spaulding, for the EMERGE investigatorsBackgroundIn adults, the most common cause of out-of-hospital cardiac arrests (OHCA) is acute coronary artery occlusion. If an immediate coronary angiogram (CAG) is recommended for survivors presenting a ST...
Authors: Gu Y, Zhang Y, Luo M, Zhang H, Liu X, Miao C Abstract BACKGROUND To study the risk predictors of intracranial asymptomatic small aneurysm rupture by electrocardiographic (ECG)-gated 4D-CT angiography (4D-CTA). MATERIAL AND METHODS A total of 168 patients with intracranial aneurysms
Publication date: Available online 17 January 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Assaf Graif, George Kimbiris, Christopher J. Grilli, Demetrios J. Agriantonis, Samuel G. Putnam, Daniel A. LeungAbstractPurposeTo examine the safety of therapeutic-dose anticoagulation during catheter-directed thrombolysis (CDT) for acute pulmonary embolism (PE).Materials and MethodsA retrospective review of 156 consecutive cases (age, 56.6 ± 15.4 years; 85 males) of CDT with alteplase for acute PE (symptoms,
ConclusionsTest and control devices demonstrated excellent patency in an ovine model. Compared to the control, test devices exhibited significantly lower %DS values at 180 days and significantly lower mid-device NC scores at 30, 90, and 180 days.