Talking About Cancer, Or Not

I have a lot of friends these days who have had cancer. And then I have friends who have not had cancer but sometimes we still talk about cancer or my health. But then I have friends who do not have cancer or any big ailments and don't really know about the disasters of my health so we talk about other things. Like life.Recently, through the wonders of social media, I reconnected with two old friends from high school who I hadn't seen in decades. I have sort of told them about all my health issues. But definitely not all of them. I have gotten together with one or both of them a few times.I got together with the one who I was closest too in high school for coffee a few weeks ago. An hour and 45 minutes flew by. We talked about her mother and her siblings. We talked about her daughters. We talked about life in the area - she lives about a mile or so from us.We decided we need to get together more often and made plans for our next meeting. And we never talked about my health. It was really nice. I need to do that more often.Further proof there is life outside of cancer crap (and if its cancer, its crap).It also made me think that I need to do that more often. I need to have conversations that allow me to focus on my life outside of my health.
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: cancer awareness quality of life Source Type: blogs

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ConclusionsIn summary, this study provides the first characterization of fusion genes in a cohort of TNBC and HGSOC patients. An improved mechanistic understanding of fusion genes will support the future identification of innovative therapeutic approaches for these challenging diseases.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsAchieving pCR after neoadjuvant chemotherapy was associated with clinically meaningful improvements in survival parameters in a real-world setting. The cumulative data support pCR as a valid surrogate endpoint in both clinical trials and population-based settings.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
British Journal of Cancer, Published online: 28 January 2020; doi:10.1038/s41416-020-0729-6Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation
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ConclusionWe developed a 12-gene prognostic signature, providing novel insights into the identification of breast cancer with a high risk of death and assessment of the possibility of immunotherapy incorporation in personalized breast cancer management.
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Clinicians should be prepared to discuss limited data for benefit of endocrine tx in ER - low positive cases
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Conclusion: it was difficult to experience and accept changes in work activities. The support of family, friends and coworkers was paramount to cope with this process, which should also be taken into account by the health team, especially nursing.RESUMO Objetivo: compreender o significado das atividades de trabalho para mulheres jovens com c âncer de mama. Método: estudo qualitativo que utilizou como referencial teórico o Interacionismo Simbólico e, metodológico, o Discurso do Sujeito Coletivo. Desenvolvido em um ambulatório de mastologia e em um núcleo de reabilitaç&a...
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Might the Breast Cancer Index effectively predict benefit from extended endocrine treatment? Data from the aTTom trial provides insight.Annals of Oncology
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MONDAY, Jan. 27, 2020 -- In an American Society of Clinical Oncology/College of American Pathologists updated guideline, published online Jan. 13 in the Archives of Pathology&Laboratory Medicine and the Journal of Clinical Oncology,...
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Undergoing earlier menopause is a sign of a greater burden of age-related damage and dysfunction, so it should not be surprising to see that this correlates with a greater incidence of chronic disease in the years thereafter. People with a greater burden of cell and tissue damage tend to exhibit all of the manifestations of aging earlier than their less damaged peers. These variations in damage burden and consequences from individual to individual are near all the results of lifestyle choices, particularly smoking, weight, and exercise, and environmental factors such as exposure to chronic viral infection. Genetics plays o...
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