IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro.

CONCLUSION: Treatment with IRF5 siRNA can reverse the pancreatitis-induced activation of lung macrophages from M1 phenotype to M2 phenotype in SAP associated with ALI.
PMID: 27895424 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - November 13, 2016 Category: Gastroenterology Authors: Sun K, He SB, Qu JG, Dang SC, Chen JX, Gong AH, Xie R, Zhang JX Tags: World J Gastroenterol Source Type: research