Repeated decrease of CD4+ T-cell counts in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

Significant peripheral blood CD4+ T-cell depletion has been observed after a first cycle of rituximab, a monoclonal antibody directed against the CD20 antigen, which is currently used in rheumatoid arthritis. ...

Source: Arthritis Research and Therapy - October 28, 2016 Category: Rheumatology Authors: Matthieu Lavielle, Denis Mulleman, Philippe Goupille, Cl ément Bahuaud, Hsueh Cheng Sung, Hervé Watier and Gilles Thibault Source Type: research