Tumorcytogenetic Diagnostics and Research on Blood and Bone Marrow Smears or Effusions

Blood smears, bone marrow smears, and effusions can be very helpful for quick molecular cytogenetic diagnostics in leukemia, lymphoma, or even solid tumors. Such samples can be studied by suited interphase FISH probes or probe sets for diagnostics, prognostics, therapeutic decisions, follow-up and control of effects of medication, or success of bone marrow transplantation. Here two protocols are provided on how to prepare smears or cell suspension in methanol/acetic acid (3:1) for subsequent FISH analyses.

Source: Springer protocols feed by Cell Biology - October 20, 2016 Category: Cytology Source Type: news