Impact of regurgitation on health-related quality of life in gastro-oesophageal reflux disease before and after short-term potent acid suppression therapy

Conclusions
Frequent regurgitation was associated with a clinically relevant, incremental decline in HRQOL beyond that associated with heartburn before and after potent acid suppression in both NERD and RO.

Clinical trial numbers
NCT00206284 and NCT00206245.

Source: Gut - April 7, 2014 Category: Gastroenterology Authors: Kahrilas, P. J., Jonsson, A., Denison, H., Wernersson, B., Hughes, N., Howden, C. W. Tags: Dyspepsia, Gastro-oesophageal reflux Oesophagus Source Type: research