α-glucosidase Inhibitory Activity of Shorea belangeran of Kerangas Forest

Conclusion: The bioactivity identification of some tree species is an important step to have a high economical value of Kerangas forest.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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DIABETES type 2 risk could be lowered by making some diet or lifestyle changes. You could lower your chances of developing high blood sugar symptoms and signs by adding this “strange” diabetes superfood to your diet.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The number of foot and leg amputations linked to diabetes has risen almost 20 per cent in only four years, according to Public Health England. Robert Carew Hunt, 69, had his left foot amputated in 2015
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This study describes a preconception biomarker risk score that may help identify women at high risk for developing gestational diabetes.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Publication date: Available online 16 December 2018Source: Redox BiologyAuthor(s): Mateusz A. Stochelski, Tomasz Wilmanski, Mitchell Walters, John R. BurgessAbstractDiabetes mellitus is one of the most common chronic diseases in the United States and peripheral neuropathy (PN) affects at least 50% of diabetic patients. Medications available for patients ameliorate symptoms (pain), but do not protect against cellular damage and come with severe side effects, leading to discontinued use. Our research group uses differentiated SH-SY5Y cells treated with advanced glycation end products (AGE) as a model to mimic diabetic condit...
Source: Redox Biology - Category: Biology Source Type: research
Authors: Harsch IA, Kaestner RH, Konturek PC Abstract Insulinotropic oral antidiabetics (OAD) such as sulfonylureas and (SU) glinides are among the frequently prescribed OAD. Side effects are the potential to induce hypoglycemias and weight gain. The aim was to assess the self-managing skills in case of a hypoglycemic event in an elderly type 2 diabetic patient population. In a 2-year period, 160 hospitalized patients (mean age 77.4 years) under insulinotrophic OAD were interviewed using a standardized questionnaire. Additionally, possible dementia was evaluated by using the Mini-Mental State Examination (MMSE) and...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Karczewski J, Śledzińska E, Baturo A, Jończyk I, Maleszko A, Maleszko A, Samborski P, Begier-Krasińska B, Dobrowolska A Abstract The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the d...
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
Authors: Bastard JP, Fellahi S, Audureau É, Layese R, Roudot-Thoraval F, Cagnot C, Mahuas-Bourcier V, Sutton A, Ziol M, Capeau J, Nahon P Abstract An obesity-related altered adipose tissue secretion is suggested as a risk factor for hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV) cirrhosis. However, no prospective study has yet examined the predictive value of circulating adipokines and immuno-inflammatory biomarkers regarding this risk. This was a case-control study nested in a prospective French national cohort of HCV-infected patients with biopsy-proven compensated cirrhosis. We se...
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
CONCLUSIONS: The data of this post-marketing study meet the request by the French authorities for additional data on conditions of use in everyday practice. They confirmed the tolerance and long-term effect of capsaicin 8% patch in patients with peripheral neuropathic pain in real-world conditions. PMID: 30550354 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
CONCLUSION: Uncapping the iGlar dose in LixiLan-O and LixiLan-L would not have led to significant improvements in mean A1C reduction in the iGlar arm, supporting the conclusion that iGlarLixi provides additional, clinically-relevant glycemic control versus iGlar alone. PMID: 30550345 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
CONCLUSIONS: Compared with BIAsp30, BIAsp50 showed greater efficacy in patients with baseline BG excursion>7.8 mmol/L or 2hPBG>17.6 mmol/L as well as good safety for hypoglycaemia. CLINICAL TRIAL REGISTRATION: ChiCTR-IIR-16008958. PMID: 30550344 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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