α-glucosidase Inhibitory Activity of Shorea belangeran of Kerangas Forest

Conclusion: The bioactivity identification of some tree species is an important step to have a high economical value of Kerangas forest.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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(MedPage Today) -- San Diego operator now under investigation by his affiliated hospital
Source: MedPage Today Nephrology - Category: Urology & Nephrology Source Type: news
Our weekly series of diabetes humor at DiabetesMine features a cartoon by Jerry King.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
This study indicates that frailty and other age-related diseases could be prevented and significantly reduced in older adults. Getting our heart risk factors under control could lead to much healthier old ages. Unfortunately, the current obesity epidemic is moving the older population in the wrong direction, however our study underlines how even small reductions in risk are worthwhile." The study analysed data from more than 421,000 people aged 60-69 in both GP medical records and in the UK Biobank research study. Participants were followed up over ten years. The researchers analysed six factors that could impa...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This article published in 2015 discusses some of the negative issues that have been associated with sitting including: Impeded cardiovascular and metabolic function Depression and psychological distress (for example, a “mental funk”) Spike in blood sugar levels Increased risk for heart attack, type 2 diabetes, insomnia, arthritis, certain types of cancers, and premature death As you can see, this list is comprised of serious issues, and the author of the article gives some great suggestions for reducing your time sitting as well as for combating sitting’s negative effects. It is interesting to note tha...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Health-related Source Type: blogs
Authors: Kadado AJ, Grewal V, Feghali K, Hernandez-Montfort J Abstract Despite major advancements since its first description in the 19th century, infective endocarditis remains a significant medical challenge. Although commonly involving a single valve, multiple valve involvement may occur, complicating matters even further. Triple-valve endocarditis is a very rare phenomenon. Poorly studied and described only a handful of times in the literature, little is known about the optimal therapeutic and management options in dealing with this complex entity. In this paper we describe the case of a 48-year-old male who wa...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Conclusion Retinal sensitivity at the central 10° of the macula is affected by changes in HbA1c values.
Source: Journal of Optometry - Category: Opthalmology Source Type: research
This study aimed to ascertain antidiabetic potential of methanolic extract of Pseuduvaria macrophylla bark (PM) using streptozotocin-nicotinamide induced diabetic rat models. Various phytochemical and biochemical properties of the plant have been evaluated. The results showed that the extract has potentially normalized the elevated blood glucose levels by upregulating the insulin and C-peptide levels and alleviated oxidative stress by improving glutathione (GSH) and reducing lipid peroxidation (LPO) in the diabetic rats. In addition, PM has drastically downregulated the levels of pro-inflammatory cytokines and transforming...
Source: Journal of Applied Biomedicine - Category: Biotechnology Source Type: research
AbstractDiabetic nephropathy patients (DN) are characterized by increased lysine63 ubiquitination (Lys63-Ub) at the tubular level. Autophagy is deregulated under diabetic conditions, even though the molecular mechanisms and the consequences of this alteration need to be elucidated. The aim of this study was to investigate the link between Lys63-Ub and autophagy in DN and the involvement of these two processes in tubular cell fate. Immunohistochemistry of beclin-1, LC3, and p62 on kidney biopsies highlighted increased protein expression of all these autophagic factors at the tubular level in DN compared to other nephritis. ...
Source: Journal of Molecular Medicine - Category: Molecular Biology Source Type: research
Written by Pendell Meyers, with edits by Steve SmithA man in his 50s with history of CAD s/p CABG, CHF, and COPD presented after several falls attributed to acute generalized weakness.  Several had reportedly resulted in head trauma.  There was a normal neurologic exam.Here is his ECG:What do you think?Sinus rhythm at around 60 bpm. There is STD with " down-up " T-waves in V2-V6, or more accurately T-wave inversion followed by large U-waves. The morphology is classic for hypokalemia. The computerized QT interval and QTc were 676ms and 663ms, which is really a measure of the Q-U interval instead of the Q...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Publication date: 15 July 2018 Source:Molecular and Cellular Endocrinology, Volume 470 Author(s): Leila Valanejad, Mwlod Ghareeb, Stephanie Shiffka, Christina Nadolny, Yuan Chen, Liangran Guo, Ruchi Verma, Sangmin You, Fatemeh Akhlaghi, Ruitang Deng Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ4-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulating body metabolism and energy expenditure. Currently, our understanding on AKR1D1 regulation and its roles in metabolic dis...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
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