Diagnostic Guidelines for Fetal Alcohol Syndrome Updated Diagnostic Guidelines for Fetal Alcohol Syndrome Updated

Proposed updates to diagnostic guidelines for fetal alcohol spectrum disorders reflect advancements in understanding of the cognitive, behavioral, and physical distinctions of these disorders.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news

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Publication date: Available online 20 July 2018Source: NeuroscienceAuthor(s): Shivakumar Subbanna, Vikram Joshi, Balapal S. BasavarajappaAbstractPostnatal ethanol exposure has been shown to cause persistent defects in hippocampal synaptic plasticity and disrupt learning and memory processes. However, the mechanisms responsible for these abnormalities are less well studied. We evaluated the influence of postnatal ethanol exposure on several signaling and epigenetic changes and on expression of the activity-regulated cytoskeletal (Arc) protein in the hippocampus of adult offspring under baseline conditions and after a Y-maze...
Source: Neuroscience - Category: Neuroscience Source Type: research
Abstract Diagnostic assessment in Fetal Alcohol Spectrum Disorder (FASD) is informed by multidisciplinary assessment incorporating objective (i.e., test measures) and subjective means, such as parent and teacher behavior ratings. The purpose of this study was to extend our previous neuropsychological test findings by identifying parent and teacher ratings of academic achievement, attention, executive functioning, and adaptive functioning as predictors of an FASD diagnosis. The charts of 315 children and adolescents with prenatal alcohol exposure (PAE) who underwent assessment for FASD were retrospectively reviewed...
Source: Child Neuropsychology - Category: Child Development Authors: Tags: Child Neuropsychol Source Type: research
ConclusionsThe replication and extension of the math intervention appears to have significant, positive impact on mathematics achievement scores of children with PAE and FASD.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
This study examined the predictive validity of...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Neuroinflammation and microglial activation have been implicated in both alcohol use disorders (AUD) and fetal alcohol spectrum disorders (FASD). Chemokine monocyte chemoattractant protein 1 (MCP-1) and its re...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
CONCLUSIONS: While understanding their milieu, our study also unraveled different struggles (such as violence, peer pressure, financial burden and depression) encountered by Native women in their daily lives. According to the participants, positive aspects of drinking outweigh the negative aspects and they viewed their drinking as a solution and not a problem. This article is protected by copyright. All rights reserved. PMID: 29972869 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
CONCLUSIONS: Mutation of the nNOS gene substantially increases vulnerability to alcohol-induced cell loss in a brain region where the gene is expressed (olfactory bulb), but not in a separate brain region, where the gene is not expressed (facial nucleus). Thus, differences in genotype may explain why some individuals are vulnerable to FASD, while others are not, and may determine the specific patterns of neuropathology in children with FASD. This article is protected by copyright. All rights reserved. PMID: 29957842 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
“A crisis is a terrible thing to waste,” is a phrase coined by Stanford economist Paul Romer. Politicians are always in search of new crises to address—new fires to put out—with rapid and decisive action. In their passion to appear heroic to their constituents they often act in haste, not ta king the time to develop a deep and nuanced understanding of the issue at hand, insensitive to the notion that their actions might actually exacerbate the crisis.An example of that lack of understanding was made apparent in a  press release by the office of House Majority Whip Steve Scalise (R-LA) on J...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
CONCLUSIONS: Combined morphology analysis of the caudate nucleus, and the corpus callosum, with the face, better identify those with FAS. Caudate nucleus asymmetry was reduced for FAS compared to controls and is strongly associated with general cognitive ability, verbal learning and recall in those with prenatal alcohol exposure. This study further extends the brain-behavior relationships known to be vulnerable to alcohol teratogenesis. This article is protected by copyright. All rights reserved. PMID: 29935097 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
In this study, ethanol-dams voluntarily consumed a 0.066% saccharin-sweetened 10% ethanol (EtOH) solution for 10 days prior to pregnancy and throughout gestation while control-dams had ad libitumaccess to a 0.066% saccharin (sacc) solution. Whole litters were randomly assigned to undergo maternal separation (MS) for 3 hours/day from P2 to P14 while the remaining litters were left undisturbed (nMS). This resulted in 4 experimental groups: control (sacc + nMS), MS (sacc + MS), EtOH (EtOH + nMS) and EtOH + MS. Throughout development, EtOH-rats weighed less than control rats. However, subsequent maternal sepa...
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research
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