Hydrophobically modified chitosan gauze: a novel topical hemostat

Currently, the standard of care for treating severe hemorrhage in a military setting is Combat Gauze (CG). Previous work has shown that hydrophobically modified chitosan (hm-C) has significant hemostatic capability relative to its native chitosan counterpart. This work aims to evaluate gauze coated in hm-C relative to CG as well as ChitoGauze (ChG) in a lethal in  vivo hemorrhage model.

Source: Journal of Surgical Research - July 26, 2016 Category: Surgery Authors: Apurva Chaturvedi, Matthew B. Dowling, John P. Gustin, Thomas M. Scalea, Srinivasa R. Raghavan, Jason D. Pasley, Mayur Narayan Source Type: research