Sézary Syndrome in a 17‐Year‐Old Boy: Clinicopathologic Features and Genomic Profile

We describe the case of a 17‐year‐old Hispanic boy who had had erythroderma and diffuse lymphadenopathy for approximately 6 months. A diagnosis of Sézary syndrome was made on the basis of the histologic features of the skin; the presence of the same T‐cell clone on the skin, blood, and bone marrow; and the high CD4+ lymphocyte count with an aberrant phenotype in peripheral blood; bone marrow involvement was also present. The patient was treated with systemic gemcitabine and achieved partial remission.

Source: Pediatric Dermatology - July 10, 2016 Category: Dermatology Authors: Silvia Alberti‐Violetti, Pamela Vezzoli, Laura Corti, Daniele Fanoni, Valentina Merlo, Luigia Venegoni, Alberto Reseghetti, Emilio Berti Tags: Case Report Source Type: research