Non-classical congenital adrenal hyperplasia in childhood.

NON-CLASSICAL CONGENITAL ADRENAL HYPERPLASIA IN CHILDHOOD. J Clin Res Pediatr Endocrinol. 2016 Jun 29; Authors: Kurtoğlu S, Hatipoğlu N Abstract Congenital adrenal hyperplasia (CAH) describes a group of autosomal recessive disorders resulting from the deficiency of enzymatic activity for the synthesis of cortisol and mineralocorticoid. There are different clinical forms of CAH regarding to enzymatic activity. This disease is classified in 2 main groups as classical and non classical. In classical type, the most severe form comprises both salt-wasting and simple virilising forms. In the non classical form, diagnosis can be more confusing because it may be asymptomatic or associated with sings of androgen excess in postnatal or even adult period. In this article, clinical findings, symptoms, diagnostic and treatment approaches and the processes of non-classical CAH types will be reviewed. PMID: 27354284 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research