HyperRAB (Rabies Immune Globulin Human) for Intramuscular Administration) - updated on RxList

Source: RxList - New and Updated Drug Monographs - Category: Drugs & Pharmacology Source Type: news

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Publication date: Available online 18 March 2019Source: BiologicalsAuthor(s): Shuyun Qin, Dmitriy Volokhov, Elvira Rodionova, Christoph Wirblich, Matthias J. Schnell, Vladimir Chizhikov, Alena DabrazhynetskayaAbstractThe Rapid Fluorescent Focus Inhibition Test (RFFIT) is a standard assay used to detect and assess the titers of rabies virus neutralizing antibodies (RVNA) in blood sera. To simplify the multistep RFFIT procedure by eliminating the immunostaining step, we generated a new recombinant RV expressing a green fluorescent protein (rRV-GFP) and assess its suitability for quantifying RVNA. We rescued the rRV-GFP virus...
Source: Biologicals - Category: Biology Source Type: research
Bats are an important ecological group within ecosystems. The rabies virus is a Lyssavirus, and haematophagous bats are the principal reservoir; however, the virus has also been detected in non-haematophagous bat...
Source: Annals of Clinical Microbiology and Antimicrobials - Category: Microbiology Authors: Tags: Research Source Type: research
Seventy-two canine serum samples were analyzed for post-vaccination serum titers of rabies antibodies. The samples were divided into two groups: Group 1 dogs (n  = 36) were imported dogs from the Russian Federa...
Source: Acta Veterinaria Scandinavica - Category: Veterinary Research Authors: Tags: Brief communication Source Type: research
H. Zhao et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Health officials are warning people to vaccinate their pets and to stay away from raccoons and other wild animals that can carry rabies
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Lateral habenula (LHb) neurons are activated by negative motivational stimuli and play key roles in the pathophysiology of depression. Prior reports suggested that rostral entopeduncular nucleus (rEPN) neurons drive these responses in the LHb and rostromedial tegmental nucleus (RMTg), but these influences remain untested. Using rabies viral tracers, we demonstrate disynaptic projections from the rEPN to RMTg, but not VTA, via the LHb in rats. Usingin vivoelectrophysiology, we find that rEPN or LHb subpopulations exhibit activation/inhibition patterns after negative/positive motivational stimuli, similar to the RMTg, while ...
Source: eLife - Category: Biomedical Science Tags: Neuroscience Source Type: research
Years after an outbreak was stamped out, rabies has returned to the raccoons of New York City.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Dogs can’t get autism, and even if they could, vaccines couldn’t cause it. Period. But some anti-vaxxers are increasingly making the same unfounded claims about pets and vaccines they’ve been repeating about children and vaccines for the past 20 years: that vaccines are unnecessary, dangerous and that they can cause a form of (canine) autism, along with other diseases. Just as with kids, that may be driving down pet vaccination rates. And the movement, while niche, shows no sign of stopping; in some states in the U.S., anti-vax activists have recently agitated to make state laws about mandatory pet vaccin...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized onetime Pets Source Type: news
Zhaochen Luo, Yingying Li, Ming Zhou, Lei Lv, Qiong Wu, Chen Chen, Yachun Zhang, Baokun Sui, Changchun Tu, Min Cui, Huanchun Chen, Zhen F. Fu, Ling Zhao
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
by Andrew J. Basinski, Scott L. Nuismer, Christopher H. Remien Zoonotic pathogens such as Ebola and rabies pose a major health risk to humans. One proven approach to minimizing the impact of a pathogen relies on reducing its prevalence within animal reservoir populations using mass vaccination. However, two major challenges remain for vaccination programs tha t target free-ranging animal populations. First, limited or challenging access to wild hosts, and second, expenses associated with purchasing and distributing the vaccine. Together, these challenges constrain a campaign’s ability to maintain adequate levels of ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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