IWO Algorithm Based on Niche Crowding for DNA Sequence Design

In this study, we specify appropriate constraints that should be satisfied in the design of DNA sequences and we propose evaluation formulae. We employ the Invasive Weed Optimization (IWO) algorithm and the niche crowding in the algorithm to solve the DNA sequence design problem. We also improve the spatial dispersal in the traditional IWO algorithm. Finally, we compared the sequences obtained with existing sequences based on the results obtained using a comprehensive fitness function, which demonstrated the efficiency of the proposed method.

Source: Interdisciplinary Sciences, Computational Life Sciences - March 24, 2016 Category: Bioinformatics Source Type: research