Vitamin D and its receptor regulate lipopolysaccharide‐induced transforming growth factor‐β, angiotensinogen expression and podocytes apoptosis via the nuclear factor‐κB pathway

ConclusionsVitamin D and its receptor may be involved in the progression of diabetic nephropathy by regulating transforming growth factor‐β, angiotensinogen expression and apoptosis of podocytes. The processes are mediated via the signaling of nuclear factor ‐κB pathway.This article is protected by copyright. All rights reserved.

Source: Journal of Diabetes Investigation - January 1, 2016 Category: Endocrinology Authors: Lijuan Xu, Pengyuan Zhang, Hongyu Guan, Zhimin Huang, Xiaoying He, Xuesi Wan, Haipeng Xiao, Yanbing Li Tags: Original Article Source Type: research