Methods to Investigate the Role of Toll-Like Receptors in Allergic Contact Dermatitis

Allergic contact disease is a common inflammatory skin disease resulting from hyperresponsiveness to harmless nonprotein substances such as metals, fragrances, or rubber. Recent research has highlighted a prominent role of Toll-like receptors, particularly TLR4 in contact allergen-induced innate immune activation that crucially contributes to the pathogenesis of this disease.
Source: Springer protocols feed by Immunology - Category: Allergy & Immunology Source Type: news