Personalized--Not Omitted--Radiation Oncology for Breast Cancer CORRESPONDENCE
How do alcohol consumption and smoking interact with familial risk for breast cancer?Breast Cancer Research
ConclusionsmiRNA ‐96‐5p may exert a tumor promotion role through negatively regulating tumor suppressor gene FOXO3 and promoting cell proliferation.
This study evaluated the time to initiation and completion of treatment in breast cancer patients undergoing neoadjuvant chemotherapy (NAC) vs adjuvant chemotherapy. We found that NAC did not expedite the start or completion of treatment. AbstractBackground/ObjectiveDelays in times to surgery, chemotherapy, and radiotherapy impair survival in breast cancer patients. Neoadjuvant chemotherapy (NAC) confers equivalent survival to adjuvant chemotherapy (AC), but it remains unknown which approach facilitates faster initiation and completion of treatment.MethodsWomen ≥18 years old with nonrecurrent, noninflammatory, clin...
In conclusion, XIST interacts with miR-454 to inhibit cells proliferation, EMT and induce apoptosis in TNBC, indicating a promising treatment strategy for TNBC patients. PMID: 32098924 [PubMed - in process]
A distinct core ‐multitentacle nanoassembly is developed utilizing small gold nanoparticles (NPs) with limited plasmon resonance in the near‐infrared (NIR). 5 nm NPs assembled as tentacles are attached to 15 nm core using multiarm polymers. They provide an intense broadband absorbance throughout the NIR “opti cal biological window” over‐and‐above that of a core–satellite. Additionally, a strong surface‐enhanced Raman scattering enhancement makes them potential candidates for optical theranostics. AbstractOptical theranostic applications demand near ‐infrared (NIR) localized surface plasmon res...
New observations of acoustic streaming generated by cells are reported. When an adherent cell is exposed to acoustic waves, oscillations of the cell cause microstreaming flow in the surrounding liquid. The observations suggest that the maximum streaming velocity generated by a cell increases with cell stiffness, and therefore, can be considered as a label ‐free strategy for probing cell mechanical properties. AbstractThe interaction of a sound or ultrasound wave with an elastic object, such as a microbubble, can give rise to a steady ‐state microstreaming flow in its surrounding liquid. Many microfluidic strategies for...
Conclusions: Patients showing a clinical benefit during 6 cisplatin-doublet chemotherapy cycles may have a sustained survival benefit from single-maintenance chemotherapy. PMID: 32098457 [PubMed - as supplied by publisher]
Publication date: Available online 26 February 2020Source: Meta GeneAuthor(s): Salma Begum Bhyan, YongKiat Wee, Mingyu Luo, Yining Liu, Min Zhao
The study found that for women with "triple-negative" breast cancer, adding Keytruda to standard chemotherapy improved their odds of responding.
Some companies are marketing the nipple aspirate test as the latest and greatest tool in early breast cancer screening. But FDA warns that the nipple aspirate test is no substitute for a mammogram. Find out why.