Immunoexpression of vascular endothelial growth factor in gingival mucosa with papilloma and condyloma acuminata.

Immunoexpression of vascular endothelial growth factor in gingival mucosa with papilloma and condyloma acuminata. Rom J Morphol Embryol. 2015;56(3):1077-1083 Authors: Scrieciu M, MercuŢ V, Andrei OC, Predescu AM, Niculescu M, Pisoschi CG, BaniŢă IM Abstract The histological changes of the oral mucosa in contact with a metal alloy dentures is one of the current issues widely debated in the literature. AIM: To highlight the expression of vascular endothelial growth factor (VEGF) in human paraprosthetic gingival mucosa exposed to nickel and copper compounds using the immunohistochemical technique. The selected participants were wearers of fixed dentures made of nickel-based alloys and copper-based alloys. The gingival mucosa fragments were prelevated through excision after removing fixed denture and extraction one of its affected teeth. The gingival mucosa fragments were processed through the histological technique of paraffin inclusion. The paraffin-embedded tissue sections were usually stained with Hematoxylin-Eosin and processed by immunohistochemical technique with VEGF antibody. The gingival mucosa fragments from nickel-based alloys dentures wearers were diagnosed with papilloma and, also, gingival mucosa samples prelevated from copper-based alloys dentures wearers were diagnosed with condyloma acuminata. Immunohistochemical reaction for VEGF was different in the gingival mucosa fragments with papilloma compared with con...
Source: Romanian Journal of Morphology and Embryology - Category: Journals (General) Tags: Rom J Morphol Embryol Source Type: research