Presence of HLA-B27 is associated with changes of serum levels of mediators of the Wnt and hedgehog pathway

Conclusions Changes in key regulators of the Wnt pathway as well as IHH, a molecule regulating endochondral ossification, are found in HLA-B27 carriers, independent if they were healthy or affected by uveitis or SpA.

Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research