Abstract 1714: The role and mechanism of JAB1 as a therapeutic target in biliary tract cancer

Conclusion: Suppression of Jab1 shows antitumor effects in BTC cells by inhibiting cell proliferation, migration, cell cycle and increase of chemosensitivity. Taken together, Jab1 might be a potential therapeutic target in BTC.Citation Format: Ah-Rong Nam, Kyo Hwa Kang, Ji Eun Park, Ju-Hee Bang, Ling Jin, Mei Hua Jin, Tae Yong Kim, Sae-Won Han, Sang-Hyun Song, Seock-Ah Im, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang. The role and mechanism of JAB1 as a therapeutic target in biliary tract cancer. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 1714. doi:10.1158/1538-7445.AM2015-1714

Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Nam, A.-R., Kang, K. H., Park, J. E., Bang, J.-H., Jin, L., Jin, M. H., Kim, T. Y., Han, S.-W., Song, S.-H., Im, S.-A., Kim, T.-Y., Oh, D.-Y., Bang, Y.-J. Tags: Experimental and Molecular Therapeutics Source Type: research