Congenital and hereditary nail disease

Actas Dermosifiliogr. 2024 Apr 23:S0001-7310(24)00341-7. doi: 10.1016/j.ad.2024.04.002. Online ahead of print.ABSTRACTNail disorders in newborns can show independently or as components of systemic illnesses or genodermatoses. The examination of these abnormalities is complex and sometimes challenging. However, familiarity with these disorders can significantly contribute to uncovering potential underlying conditions. This review includes the physiological nail changes seen within the first few months of life, such as Beau's lines, onychoschizia, koilonychia, congenital nail fold hypertrophy of the first digit, and onychocryptosis. This review also focuses on the most relevant congenital disorders reported and how to perform differential diagnosis. Finally, this review highlights those hereditary diseases in which nail involvement is crucial for diagnosis, such as nail-patella syndrome, congenital pachyonychia, or congenital dyskeratosis, among others.PMID:38663727 | DOI:10.1016/j.ad.2024.04.002

Source: Actas Dermo-Sifiliograficas - April 25, 2024 Category: Dermatology Authors: L Bernal Masferrer M Claudia Matei Y Gilaberte Calzada L Navarro Campoamor Source Type: research