NIR-II light in clinical oncology: opportunities and challenges

Nature Reviews Clinical Oncology, Published online: 01 May 2024; doi:10.1038/s41571-024-00892-0Expansion of the utilizable spectrum of light from the visible region to the near-infrared (NIR) window has greatly facilitated the clinical application of optical technologies for cancer imaging and phototherapy. However, use of light in the first NIR region (NIR-I) has important limitations, some of which might be overcome with emerging technologies utilizing NIR-II light. In this Review, the authors describe the current clinical experience with NIR-II-based cancer imaging and phototherapy, and discuss emerging NIR-II-based approaches that might further enhance patient outcomes. They also highlight challenges that will need to be addressed to translate NIR-II-based modalities from bench to bedside.

Source: Nature Reviews Clinical Oncology - May 1, 2024 Category: Cancer & Oncology Authors: Zeyu Zhang Yang Du Xiaojing Shi Kun Wang Qiaojun Qu Qian Liang Xiaopeng Ma Kunshan He Chongwei Chi Jianqiang Tang Bo Liu Jiafu Ji Jun Wang Jiahong Dong Zhenhua Hu Jie Tian Source Type: research