Electrophotocatalysis versus Indirect Electrolysis: Electrochemical Selenocyclization of 3-Aza-1,5-dienes Facilitated by Energy Transfer, Direct Photolysis or N-Hydroxyphthalimide

Chemistry. 2024 Apr 23:e202400280. doi: 10.1002/chem.202400280. Online ahead of print.ABSTRACTThree hybrid electrochemical protocols, which involve the energy transfer, direct photolysis and N-hydroxyphthalimide catalyst, respectively, are presented for the selenylation/cyclization of the fragile substrates of 3-aza-1,5-dienes with diorganyl diselenides to afford 3-selenomethyl-4-pyrrolin-2-ones. The two electrophotocatalytic reactions and the indirect electrolysis one are both regioselective and external-oxidant- and transition-metal-free, and are associated with a broad substrate scope and high Se-economy, and all three methods are amenable to gram-scale syntheses, late-stage functionalizations, sunlight-induced experiments and all-solar-driven syntheses.PMID:38651795 | DOI:10.1002/chem.202400280

Source: Chemistry - April 23, 2024 Category: Chemistry Authors: Dongyin Wang Li Zeng Jifu Shi Shulin Gao Lou Shi Shaoguang Sun Deqiang Liang Source Type: research