Polar lipids modify Alzheimer ’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation

Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (A β) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques cont...

Source: Lipids in Health and Disease - April 20, 2024 Category: Lipidology Authors: Sakshi Hans, Janelle E. Stanton, Ann Katrin Sauer, Katie Shiels, Sushanta Kumar Saha, Ronan Lordan, Alexandros Tsoupras, Ioannis Zabetakis and Andreas M. Grabrucker Tags: Research Source Type: research